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Microbiological synthesis of 5-ethyl- and (E)-5-(2-bromovinyl)-2′-deoxyuridine

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Summary

The title compounds were prepared by an enzymatic transdeoxyribosylation from 2′ dGuo or 2′ dThd to the respective heterocyclic bases, 5-ethyluracil and (E)-5-(2-bromovinyl)uracil, using the whole bacterial cells ofEscherichia coli as a biocatalyst.

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Kalinichenko, E.N., Barai, V.N., Bokut, S.B. et al. Microbiological synthesis of 5-ethyl- and (E)-5-(2-bromovinyl)-2′-deoxyuridine. Biotechnol Lett 11, 621–626 (1989). https://doi.org/10.1007/BF01025269

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  • DOI: https://doi.org/10.1007/BF01025269

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