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Quantitative treatment of a bioreactor employing a recombinant cell system — A theoretical analysis

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Summary

A theoretical analysis on the product distribution in a bioreactor employing a recombinant cell system has been made. Simulated results of a batch or plug flow reactor based on Monod's kinetics show that a higher initial concentration of plasmidless cell should be avoided to prevent rapid consumption of substrate. This enables one to get maximum concentration of metabolite, the desired product.

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References

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Author notes

  1. P. Bhattacharya

    Present address: Chemical Engineering Department, Jadavpur University, Calcutta, India

Authors and Affiliations

  1. Department of Chemical and Biochemical Engineering Rutgers, the State University of New Jersey, 08855, Piscataway, NJ

    A. Constantinides & P. Bhattacharya

Authors
  1. A. Constantinides
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  2. P. Bhattacharya
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Constantinides, A., Bhattacharya, P. Quantitative treatment of a bioreactor employing a recombinant cell system — A theoretical analysis. Biotechnol Lett 10, 231–236 (1988). https://doi.org/10.1007/BF01024411

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  • DOI: https://doi.org/10.1007/BF01024411

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