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Transition Metal Chemistry

, Volume 15, Issue 2, pp 120–125 | Cite as

Mixed-ligand complexes of gold(I) and silver(I) with heterocyclic thiones

  • M. Sakhawat Hussain
  • M. Latif Hossain
  • Abderehman Al-Arfaj
Full Papers

Summary

Novel mixed-ligand complexes of Ag1 and Au1 containing triphenylphosphine (TPP) and heterocyclic thiones, of general formula [TPP−M−L]Cl and [(TPP)2−M−L]Cl, where L=imidazolidine-2-thione (Imt), 1,3-diazinine-2-thione (Diaz) or N-isopropylimidazolidine-2-thione (iPrImt) have been prepared. The spectroscopic data are consistent with S-donation in all complexes. The magnitude of high-field shift in carbon-13 n.m.r. of the thioureide carbon on complexation is interpreted in terms of coordination geometry around the metal atoms. The mixed-ligand complexes are structurally similar to some of the commonly used antiarthritic Au1 drugs and are thus potentially useful in chemotherapy.

Keywords

PPh3 Auranofin Transition Meet Downfield Shift Trimethylphosphate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Chapman and Hall Ltd 1990

Authors and Affiliations

  • M. Sakhawat Hussain
    • 1
  • M. Latif Hossain
    • 1
  • Abderehman Al-Arfaj
    • 1
  1. 1.Department of Chemistry King Fahd University of Petroleum and MineralsDhahranSaudi Arabia

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