Biotechnology Letters

, Volume 16, Issue 1, pp 7–10 | Cite as

Effect of support matrix on ratio of product to by-product formation in L-phenylacetyl carbinol synthesis

  • Penka Nikolova
  • Owen P. Ward
Article

Abstract

Production of L-phenylacetyl carbinol (PAC) and benzyl alcohol by biotransformation from pyruvate and benzaldehyde substrates was investigated using yeast cells in different polymeric matrices. Highest concentration of PAC was produced by cells immobilised in the hydrophilic matrix, ENT-4000. Highest concentration of the by-product, benzyl alcohol, was produced in the hydrophobic matrix, ENTP-2000. Ratio of PAC to benzyl alcohol ranged from 1∶0.08 for cells entrapped in a poly(propyleneglycol)-containing polymer, PU-3, to 1∶1.8 for cells entrapped in ENTP-2000 polymer.

Keywords

Polymer Alcohol Organic Chemistry Pyruvate Yeast Cell 

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Copyright information

© Kluwer Academic Publishers 1994

Authors and Affiliations

  • Penka Nikolova
    • 1
  • Owen P. Ward
    • 1
  1. 1.Microbial Biotechnology Laboratory, Department of BiologyUniversity of WaterlooWaterlooCanada

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