Abstract
Mechanisms by which schistosomes escape host immune responses are reviewed, with particular emphasis regarding the possible contributions of host or host-like Fc and C3 receptors on adult parasites.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Auriault, C., Joseph, M., Dessaint, J.P., andCapron, A. 1980. Inactivation of rat macrophages by peptides resulting from cleavage of IgG bySchistosoma larvae proteases.Immunol. Lett. 2:135–139.
Auriault, C., Ouaissi, M.A., Torpier, G., Eisen, H., andCapron, A. 1981. Proteolytic cleavage of IgG bound to the Fc receptor ofSchistosoma mansoni schistosomula.Parasite Immunol. 3:33–44.
Campbell, D.L. 1973. The demonstration of mouse IgG and alpha-globulin associated with adultSchistosoma mansoni from infected mice.Fed. Proc. 32:1030.
Caulfield, J.P., Korman, G., Butterworth, A.E., Hogan, M., andDavid, J.R. 1980a. The adherence of human neutrophils and eosinophils to schistosomula: Evidence for membrane fusion between cells and parasites.J. Cell Biol. 86:46–63.
Caulfield, J.P., Korman, G., Butterworth, A.E., Hogan, M., andDavid, J.R. 1980b. Partial and complete detachment of neutrophils and eosinophils from schistosomula: Evidence for the establishment of continuity between a fused and normal parasite membrane.J. Cell Biol. 86:64–76.
Damian, R.T. 1964. Molecular mimicry: Antigen sharing by parasite and host and its consequences.Am. Nat. 98:129–149.
Gitter, B.D., andDamian, R.T. 1982. Murine alloantigen acquisition by schistosomula ofSchistosoma mansoni: Further evidence for the presence of K, D, and I region gene products on the tegumental surface.Parasite Immunol. 4:383–393.
Gitter, B.D., McCormick, S.L., andDamian, R.T. 1982. Murine alloantigen acquisition bySchistosoma mansoni: Presence of H2-K determinants on adult worms and failure of allogeneic lymphocytes to recognize acquired MHC gene products on schistosomula.J. Parasitol. 68:513–518.
Kabil, S.M. 1976. Host complement in the schistosomal tegument.J. Trop. Med. Hyg. 79:205–206.
Kemp, W.M., Damian, R.T., andGreene, N.D. 1976. Immunocytochemical localization of IgG on adultSchistosoma mansoni tegumental surfaces.J. Parasitol. 62:830–832.
Kemp, W.M., Merritt, S.C., Bogucki, M.S., Rosier, J.G., andSeed, J.R. 1977. Evidence for adsorption of heterospeciflc host immunoglobulin on the tegument ofSchistosoma mansoni.J. Immunol. 119:1849–1854.
Kemp, W.M., Merritt, S.C., andRosier, J.G. 1978.Schistosoma mansoni: Identification of immunoglobulins associated with the tegument of adult parasites from mice.Exp. Parasital. 45:81–87.
Kemp, W.M., Brown, P.R., Merritt, S.C., andMiller, R.E. 1980. Tegument associated antigen modulation by adult maleSchistosoma mansoni.J. Immunol. 124:806–811.
Levy-Schaffer, F., Schryer, M.D., andSomlarsky, M. 1982. The resistance of schistosomula ofSchistosoma mansoni to antibodies and complement in vitro does not correlate with the binding of antibodies to the surface of the parasite.J. Immunol. 129:2744–2751.
McGuinness, T.B., andKemp, W.M. 1981.Schistosoma mansoni: Evidence for a complement dependent receptor on adult male parasites.Exp. Parasitol. 51:236–242.
Phillips, S.M., Reid, W.A., Bruce, J.I., Hedlund, K., ColVin, R.C., Campbell, R. Diggs, C.L., andSadun, E.H. 1975. The cellular and humoral immune response toSchistosoma mansoni infections in inbred rats. I. Mechanisms during initial exposure.Cell. Immunol. 19:99–116.
Rasmussen, K.R., andKemp, W.M. 1985. Inhibition of specific antibody binding to adult maleSchistosoma mansoni by adsorbed host serum components.J. Parasitol. 71:530–534.
Santoro, F., Ouaissi, M.A., andCapron, A. 1979. Receptors for complement (Clq and C3b) on the immature forms ofSchistosoma mansoni.ICRS Med. Sci. 7:576.
Sher, A., Hall, B.F., andVadas, M.A. 1978. Acquisition of murine major histocompatibility complex gene products by schistosomula ofSchistosoma mansoni.J. Exp. Med. 148:46–57.
Smithers, S.R., Terry, R.J., andHockley, D.J. 1969. Host antigens in schistosomiasis.Proc. R. Soc. London (Biol.) 171:483–494.
Sogandares-Bernal, F. 1976. Immunoglobulins attached to and in the tegument of adultSchistosoma mansoni Sambon 1907, from first infection of CF1 mice.J. Parasitol. 62:222–226.
Stirewalt, M.A., andEvans, A.S. 1955. Serologie reactions inSchistosoma mansoni infections. I. Cercaricidal, precipitation, agglutination and CHR phenomena.Exp. Parasitol. 4:123–142.
Tarleton, R.L., andKemp, W.M. 1981. Demonstration of IgG-Fc and C3 receptors on adultSchistosoma mansoni.J. Immunol. 126:379–384.
Tavares, C.A.P., Gazzinelli, G., Mota-Santos, T.A., andDias Da Silva, W. 1978.Schistosoma mansoni: Complement-mediated cytotoxic activity in vitro and effect of decomplemen- tation on acquired immunity in mice.Exp. Parasitol. 46:145–151.
Torpier, G., Capron, A., andOuaissi, M.A. 1979. Receptor for IgG (Fc) and beta 2-microglobulin onS. mansoni schistosomula.Nature 278:447–449.
Tsang, V.C.W., andDamian, R.T. 1977. Demonstration and mode of action of an inhibitor for activated Hageman factor (factor XIIa) of the intrinsic blood coagulation pathway fromSchistosoma mansoni.Blood 49:619–633.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kemp, W.M., Tarleton, R.L., Mcguinness, T.B. et al. Biology of tegument associated IgG-Fc and C3 receptors inSchistosoma mansoni . J Chem Ecol 12, 1833–1841 (1986). https://doi.org/10.1007/BF01022387
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01022387