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Enhanced spore production ofBacillus thuringiensis by fed-batch culture

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Summary

Fed-batch culture was carried out to increase cell mass followed by batch culture for spore production ofbacillus thuringiensis. High cell mass obtained by increasing the feeding glucose concentration in constant fed-batch culture which supported fast cell growth resulted in good sporulation during subsequent batch culture, and the maximum cell mass of 72.6 g/L and spore concentration of 1.25×1010 spores/mL could be obtained.

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Authors and Affiliations

  1. BioProcess Engineering Research Center and Department of Chemical Engineering, Korea Advanced Institute of Science and Technology, 305-701, Taeduk Science Town, Taejon, Korea

    Byung Chul Kang, Sang Yup Lee & Ho Nam Chang

Authors
  1. Byung Chul Kang
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  2. Sang Yup Lee
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  3. Ho Nam Chang
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Kang, B.C., Lee, S.Y. & Chang, H.N. Enhanced spore production ofBacillus thuringiensis by fed-batch culture. Biotechnol Lett 14, 721–726 (1992). https://doi.org/10.1007/BF01021650

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  • DOI: https://doi.org/10.1007/BF01021650

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