Biotechnology Letters

, Volume 16, Issue 11, pp 1167–1172 | Cite as

Lipase catalyzed acylation of glucose

  • Gudrun Ljunger
  • Patrick Adlercreutz
  • Bo Mattiasson


Octanoylglucose was synthesized from insoluble glucose and octanoic acid in acetonitrile, using lipase fromCandida antarctica as catalyst. The initial concentration of octanoic acid was optimized to give complete conversion of glucose to monoester and avoid diester formation. The acylation occurred exclusively at the primary hydroxyl group on the glucose ring.


Glucose Hydroxyl Organic Chemistry Acetonitrile Lipase 
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Copyright information

© Kluwer Academic Publishers 1994

Authors and Affiliations

  • Gudrun Ljunger
    • 1
  • Patrick Adlercreutz
    • 1
  • Bo Mattiasson
    • 1
  1. 1.Dept. of Biotechnology, Chemical CenterUniversity of LundLundSweden

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