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Low-dose heparin in the management of acute myelocytic leukaemia

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Zusammenfassung

über die EffektivitÄt der Heparintherapie bei der akuten LeukÄmie mit Verbrauchskoagulopathie besteht noch keine einheitliche Meinung. In diesem Zusammenhang wird von drei Patienten berichtet, die mit kleinen Dosen Heparin erfolgreich behandelt wurden. Da eine hohe Heparindosierung bei der akuten LeukÄmie mit Verbrauchskoagulopathie kontraindiziert ist, scheint die niedrige Dosierung eine effektive Alternative zu sein.

Summary

The effectiveness of heparin in acute leukaemia complicated by disseminated intravascular coagulation (DIC) is still controversial. In this regard low-dose heparin was found to be therapeutically effective in three patients suffering from acute myelocytic leukaemia and DIC. With respect to the contraindication of high-dose heparin in these conditions the low dose regimen appears to be a valuable alternative.

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Authors and Affiliations

  1. UniversitÄtsklinikum (Tumorforschung), D-4300, Essen 1, Germany

    M. R. Nowrousian & P. Hilgard

Authors
  1. M. R. Nowrousian
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  2. P. Hilgard
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Additional information

P. Hilgard was supported by a grant from the Deutsche Forschungsgemeinschaft, Bonn-Bad Godesberg, F.R.G. (Hi 213/4)

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Nowrousian, M.R., Hilgard, P. Low-dose heparin in the management of acute myelocytic leukaemia. Blut 37, 341–343 (1978). https://doi.org/10.1007/BF01007869

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  • DOI: https://doi.org/10.1007/BF01007869

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