Thrombus and branch retinal vein occlusion

  • Edoardo Baglivo
  • André Dosso
  • Constantin Pournaras
Clinical Investigation


Branch retinal vein occlusion (BRVO) is often associated with arteriosclerosis. Typically the occlusion occurs at an arteriovenous crossing. We report a case of a previously healthy patient who developed a BRVO. Funduscopy and fluorescein angiography suggested an intravascular thrombus as the cause of the occlusion. The investigations performed were positive for systemic hypertension and hyperlipidaemia. After 2 months, fundus examination revealed disappearance of the intravascular thrombus, resolution of the macular edema and improvement of the — visual acuity. Certain physiological characteristics of the retinal circulation associated with hyperlipidaemia and systemic hypertension appear to favour thrombus formation.


Public Health Hypertension Visual Acuity Fluorescein Macular Edema 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Appiah AP, Greenidge KC (1987) Factors associated with retinal vein occlusions in Hispanics. Ann Ophthalmol 19: 307–309Google Scholar
  2. 2.
    Appiah AP, Trempe CL (1989) Differences in contributory factors among hemicentral, central, and branch retinal vein occlusions. Ophthalmology 96:364–366Google Scholar
  3. 3.
    Coscas G, Dhermy P (1978) Occlusions veineuses rétiniennes. (Société française d'ophtalmologie) Masson, ParisGoogle Scholar
  4. 4.
    De Gennes JL, Ozanne P, Turpin G (1982) Les accidents thrombo-emboliques veineux au cours des hyperlipidémies idiopathiques. Nouv Presse Med 23: 1777–1780Google Scholar
  5. 5.
    Dodson PM, Galton DJ, Winder AF (1981) Retinal vascular abnormalities in the hyperlipidaemias. Trans Ophthalmol Soc UK 101: 17–21Google Scholar
  6. 6.
    Dodson PM, Galton DJ, Hamilton AM, Blach RK (1982) Retinal vein occlusion and the prevalence of lipoprotein abnormalities. Br J Ophthalmol 66: 161–164Google Scholar
  7. 7.
    Duker JS, Brown GC (1989) Anterior location of the crossing artery in branch retinal vein obstruction. Arch Ophthalmol 107: 998–1000Google Scholar
  8. 8.
    Feist RM, Ticho BH, Shapiro MJ, Farber M (1992) Branch retinal vein occlusion and quadratic variation in arteriovenous crossings. Am J Ophthalmol 113: 664–668Google Scholar
  9. 9.
    Finkelstein D (1989) Retinal branch vein occlusion. In: Ryan SJ, Schachat AP, Murphy RP, Patz A (eds) Medical retina, vol 2. Mosby, St Louis, pp 427–432Google Scholar
  10. 10.
    Frangieh GT, Green R, Barraquer-Somers E, Finkelstein D (1982) Histopathologic study of nine branch retinal vein occlusions. Arch Ophthalmol 100: 1132–1140Google Scholar
  11. 11.
    Jensen VA (1936) Clinical studies of tributary thrombosis in the central retinal vein. Acta Ophthalmol Suppl 10: 1–193Google Scholar
  12. 12.
    Johnston RL, Bruckner AJ, Steinmann W, Hoffmann ME, Holmes JH (1985) Risk factors of branch retinal vein occlusion. Arch Ophthalmol 103: 1831–1832Google Scholar
  13. 13.
    Kannel WB, Castelli WP, Gordon T, et al (1971) Serum cholesterol, lipoproteins, and the risk of coronary heart disease. The Framingham study. Ann Intern Med 74: 1–11Google Scholar
  14. 14.
    Leber T (1877) Die Krankheite der Netzhaut und des Sehnerven. In: Graefe A, Saemisch T (eds) Handbuch der Gesammten Augenheilkunde: Pathologie und Therapie. Engelmann, Leipzig, pp 521–535Google Scholar
  15. 15.
    McGrath MA, Wechsler F, Hunyor AB, Penny R (1978) Systemic factors contributory to retinal vein occlusion. Arch Intern Med 138: 216–220Google Scholar
  16. 16.
    Orth DH, Patz A (1978) Retinal branch vein occlusion. Surv Ophthalmol 22: 357–376Google Scholar
  17. 17.
    Rath EZ, Frank RN, Shin DH, Kim C (1992) Risk factors for retinal vein occlusions. Ophthalmology 99: 509–514Google Scholar
  18. 18.
    The Lipid Research Clinics Coronary Primary Prevention Trial (1984) The lipid research clinics coronary primary prevention trial results. 1. Reduction in incidence of coronary heart disease. 2. The relationship of reduction in incidence of coronary heart disease to cholesterol lowering. JAMA 251: 351–364Google Scholar
  19. 19.
    Weinberg D, Dodwell DG, Fern SA (1990) Anatomy of arteriovenous crossings in branch retinal vein occlusion. Am J Ophthalmol 109:298–302Google Scholar

Copyright information

© Springer-Verlag 1997

Authors and Affiliations

  • Edoardo Baglivo
    • 1
  • André Dosso
    • 1
  • Constantin Pournaras
    • 1
  1. 1.Clinique d'OphtalmologieHôpital Cantonal UniversitaireGenevaSwitzerland

Personalised recommendations