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Succinate dehydrogenase activity in the developing molar of the hairless mouseMus musculus

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Succinate dehydrogenase activity in the odontogenic tissues of the hairless mouse (hr/hr) has been studied from the initiation of the dental lamina through apposition. Enzyme activities were designated as negative, slight, moderate and strong as a function of intensity of the reaction product. Enzyme levels in the odontogenic tissues increased with advancing tooth morphogenesis. Greatest activity was observed in the ameloblastic layer which peaked on the fourth to sixth postnatal days. This cell layer displayed higher enzyme activity than the ectomesenchymally-derived odontoblasts. Succinate dehydrogenase activity appeared to be related to the degree of differentiation and functional competence on the odontogenic tissues of the hairless mouse.

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References

  • Balogh, K., Jr. (1963). Histochemical study of oxidative enzyme systems in teeth and peridental tissues.J. dent. Res. 42, 1457–66.

    Google Scholar 

  • Barka, T. &Anderson, P. J. (1963).Histochemistry Theory, Practice and Bibliography. pp. 300–306. New York: Harper and Row.

    Google Scholar 

  • Brooke, H. C. (1926). Hairless mice.J. Hered. 17, 173–4.

    Google Scholar 

  • Burstone, M. S. (1960). Histochemical observations on enzymatic process in bones and teeth.Ann. New York Acad. Science 85, 431–44.

    Google Scholar 

  • Crew, F. A. &Mirskaia, L. (1931). The character hairless in the mouse.J. Genet. 25, 17–24.

    Google Scholar 

  • David, L. T. (1932). The external expression and comparative dermal histology of hereditary hairlessness in mammals.Z. Zellforsch. 14, 616–719.

    Google Scholar 

  • Derobertis, E. D. P., Nowinski, W. W. &Saez, F. A. (1967).Cell Biology. Philadelphia: Saunders.

    Google Scholar 

  • Flanagan, S. P. &Isaacson, J. H. (1967). Close linkage between genes which cause hairlessness in the mouse.Genet. Res. 9, 99–110.

    Google Scholar 

  • Fullmer, H. M. (1963). Dehydrogenases in developing teeth of rats.J. Histochem. Cytochem. 11, 641–64.

    Google Scholar 

  • Gaskoin, J. S. (1856). On a peculiar variety ofMus Musculus.Proc. Zool. Soc. Lond. 24, 38–40.

    Google Scholar 

  • Goggins, J. F. &Fullmer, H. M. (1966). Dehydrogenase histochemistry of the rat molar pulp.Arch. oral Biol. 11, 1365–70.

    Google Scholar 

  • Gordon, G. (1850). Variety of the common house mouse (Mus musculus).Zoologist 8, 2763–64.

    Google Scholar 

  • Hiatt, J. L. (1976). Succinate dehydrogenase activity in the developing molar of the Mongolian gerbilMeriones unguiculatus.Histocyem. J. 8, 103–12.

    Google Scholar 

  • Howard, A. (1940). Rhino, an allele of hairless in the house mouse.J. Hered. 31, 467–70.

    Google Scholar 

  • Eefninger, A. L. (1971).Bioenergetics. Menlo, California: Benjamin.

    Google Scholar 

  • Lowenstein, J. M. (1967). The tricarboxylic acid cycle. In:Metabolic Pathways. Vol. 1, (ed. D. M. Greenberg). New York: Academic Press.

    Google Scholar 

  • Malaty, H. A. &Bourne, G. H. (1953). Histochemistry of succinic dehydrogenase.Nature 171, 295–97.

    Google Scholar 

  • Mann, S. J. (1963). The phenogenetics of hair mutants in the house mouse: opossum and ragged.Genet. Res. 4, 1–11.

    Google Scholar 

  • Mori, M., Mizushima, T. &Osanai, K. (1961). The histochemical demonstration of succinic dehydrogenase activity in developing teeth.Histochemie 2, 348–55.

    Google Scholar 

  • Nachlas, M. M., Tsow, K.-C., Souza, E. D., Cheng, C.-S. &Seligman, A. M. (1957). Cytochemical demonstration of succinic dehydrogenase by the use of a new pinitrophenyl substituted ditetrazole.J. Histochem. Cytochem. 5, 420–36.

    Google Scholar 

  • Nachlas, M. M., Margulies, S. I. &Seligman, A. M. (1960). A colorimetric method for the estimation of succinic dehydrogenase activity.J. biol. Chem. 235, 499–503.

    Google Scholar 

  • Packchanian, A. &Rigdon, R. H. (1970). Papillomas (warts) in hairless mice:Mus muscuhis and Peromyscus maniculatus gambeli.Tex. Rep. Biol. Med. 28, 565–80.

    Google Scholar 

  • Payne, T. M., Gartner, L. P., Hiatt, J. L. &Provenza, D. V. (1976). The hairless mouse: A selected literature review.J. Baltimore Coll. dent. Surg. 31, 8–15.

    Google Scholar 

  • Payne, I. M., Gartner, L. P., Hiatt, J. L. &Provenza, D. V. (1977). Molar ondontogenesis in the hairless mouse.Acta. anat. 98, 264–74.

    Google Scholar 

  • Pocock, R. I. (1904).Proc. zool. Soc. Lond. 2, 133.

    Google Scholar 

  • Provenza, D. V., Chang, Y.-F., Gartner, L. P. &Garlitz, R. M. (1972). Histochemical demonstration of succinic dehydrogenase activity during sequential molar development in the Swiss albino mouse.Histochemie 29, 355–61.

    Google Scholar 

  • Rsith, E. J. &Zussman, W. V. (1964). Succinic dehydrogenase in ameloblasts during formation and maturation of enamel.Arch. oral Biol. 9, 31–8.

    Google Scholar 

  • Rosa, C. G. &Velardo, J. I. (1954). Histochemical demonstration of succinic dehydrogenase activity in tissue sections by a modified technique.J. Histochem. Cytochem. 2, 110–14.

    Google Scholar 

  • Scarpelli, D. G., Hess, R. &Pearse, A. G. E. (1958). The cytochemical localization of succinic dehydrogenase in mitochondria.Anat. Rec. 132, 133–43.

    Google Scholar 

  • Sfligman, A. M. &Rutenburg, A. M. (1951). The histochemical demonstration of succinic dehydrogenase.Science 113, 317–20.

    Google Scholar 

  • Shelton, E. &Schneider, W. C. (1952). On the usefulness of tetrazolium salts as histochemical indicators of dehydrogenase activity.Anat. Rec. 112, 61–81.

    Google Scholar 

  • Snell, G. D. (1930). Inheritance in the house mouse, the linkage relations of short ear, hairless and naked.Genetics 16, 42–72.

    Google Scholar 

  • Steinberg, A. G. &Fraser, F. C. (1946). The expression and interaction of hereditary factors affecting hair growth in mice: external observations.Can. J. Res. 24, 1–9.

    Google Scholar 

  • Sumner, F. B. (1924). Hairless mice.J. Hered. 15, 475–81.

    Google Scholar 

  • Swartz, E. M. &Yaeger, J. A. (1961). Succinic dehydrogenase activity in odontoblasts.J. dent. Res. 40, 1291.

    Google Scholar 

  • Tsuji, S. &Yosida, T. H. (1965). Reciprocal skin transplantation between normal and hereditary hairless mice.Jap. J. Genet. 40, 55–62.

    Google Scholar 

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Payne, T.M. Succinate dehydrogenase activity in the developing molar of the hairless mouseMus musculus . Histochem J 11, 639–648 (1979). https://doi.org/10.1007/BF01004728

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  • DOI: https://doi.org/10.1007/BF01004728

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