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A comparison of the PAS-reaction in the dermis of diabetic and non-diabetic humans

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Dermopathy is a part of the diabetic syndrome that decreases the solubility of dermal collagen. In the present study, the PAS-reactive component of collagen has been analysed in diabetic and non-diabetic human dermis by photographic densitometry. The PAS-reaction was significantly lower in diabetics than non-diabetics, and age seemed to be of no consequence. The results are interpreted to indicate a decrease in collagen-associated sugar residues in diabetics.

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Authors and Affiliations

  1. Department of Anatomy, Medical College of Georgia, 30902, Augusta, Georgia, USA

    T. H. Rosenquist & T. G. Oblak

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  1. T. H. Rosenquist
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  2. T. G. Oblak
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Rosenquist, T.H., Oblak, T.G. A comparison of the PAS-reaction in the dermis of diabetic and non-diabetic humans. Histochem J 10, 185–190 (1978). https://doi.org/10.1007/BF01003303

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  • DOI: https://doi.org/10.1007/BF01003303

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