The Histochemical Journal

, Volume 10, Issue 6, pp 633–640 | Cite as

Phosphorylase activity as a histochemical marker of specialized tissue of heart

  • C. L. Pathak
  • S. Goyal


Phosphorylase activity has been investigated histochemically under controlled conditions in the specialized tissue and the general myocardium of goat heart using glucose-1-phosphate as the substrate. It has been observed that the phosphorylase content of the nodal and conducting tissue is very high as compared to the general myocardium. The phosphorylase content of the cardiac neural elements is also high. Since the connective tissue which surrounds the nodal and conducting tissue has almost no phosphorylase activity, the nodal and conducting tissue is sharply demarcated by the histochemical reaction for phosphorylase. This reaction can, therefore, be used as a specific and expedient method for the localization of specialized tissue as an exploratory and confirmatory test.


Connective Tissue Specialized Tissue Phosphorylase Confirmatory Test Neural Element 
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Copyright information

© Chapman and Hall Ltd. 1978

Authors and Affiliations

  • C. L. Pathak
    • 1
  • S. Goyal
    • 1
  1. 1.Department of Physiology, Biophysics and BiochemistryS.N. Medical CollegeJodhpurIndia

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