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The action of veratridine on the membrane potential of the crayfish stretch receptor neurone

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Conclusions

The results fully support the current idea that veratridine acts on the sodium system of regenerative membranes (see review of Ulbricht, 1969). Evidence against an action of the alkaloid on generator membrane elements comes from the results (5) and (6), where no alteration of the generator potential could be observed after the addition of the drug. Therefore the results also support the hypothesis of Paintal (1964).

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Authors and Affiliations

  1. Pharmakologiscbes Institut der Justus Liebig-Universität Gießen, Deutschland

    H. H. Wellhöner

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  1. H. H. Wellhöner
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Additional information

This work was supported by grant No 111186 from the Stiftung Volkswagenwerk.

My thanks are due to Missis Heike Neumann for technical assistance and to Prof. H. Meves and Dr. W. W. Ulbricht for helpful criticism of the manuscript.

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Wellhöner, H.H. The action of veratridine on the membrane potential of the crayfish stretch receptor neurone. Naunyn-Schmiedebergs Arch. Pharmak. 267, 185–188 (1970). https://doi.org/10.1007/BF00999401

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  • DOI: https://doi.org/10.1007/BF00999401

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