Action of caerulein and related substances on the sphincter of Oddi
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The effects of caerulein and some related substances were investigated on the sphincter of Oddi which had been contracted by morphine in the guinea-pig, and on the isolated terminal bile duct in the calf. In the first test caerulein (50–100 ng/kg i.v.) was the most potent spasmolytic drug whereas in the second test the peptide (0.75-1 Μg/ml) produced actually a spasmogenic effect. The peptide resembled epinephrine in both preparations.
Key-WordsMorphine Caerulein Sphincter of Oddi
SchlüsselwörterMorphin Caerulein Sphincter Oddi
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