Die Wirkung von Pentobarbital auf die Zelltätigkeit des Nucleus Ruber

  • G. Gogolák


Pentobarbital Kaninchen Neuronentätigkeit Nucleus ruber Cerebellum 

The action of pentobarbital on the activity of single neurones of the red nucleus


The rhythmic electrical activity of the cerebellum and the electrical activity of single red nucleus neurones were recorded simultaneously in rabbits under pentobarbital anaesthesia. The following results were obtained:
  1. 1.

    Under pentobarbital, the units of the red nucleus discharge in regular bursts synchronous with the regular, barbiturate-induced electrical activity of the red nucleus and the cerebellum.

  2. 2.

    The bursts of the red nucleus neurones are correlated with the positive peak of the red nucleus rhythm as well as the positive peak of the membrane oscillations of single red nucleus neurones.

  3. 3.

    Calculations were carried out in order to determine how discharge rate and duration of bursts of single red nucleus neurones as well as frequency of red nucleus rhythm depend on pentobarbital concentration in blood.


The nature of the barbiturate-induced red nucleus rhythm is discussed on the basis of these findings.


Pentobarbital Rabbit Single Neurone Activity Red Nucleus Cerebellum 


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Copyright information

© Springer-Verlag 1970

Authors and Affiliations

  • G. Gogolák
    • 1
    • 2
  1. 1.Pharmakologisches Institut der Universität WienDeutschland
  2. 2.Institut für Hirnforschung der Österreichischen Akademie der WissenschaftenDeutschland

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