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Correlative evaluation of serum lipid, blood glucose, blood pressure, serum immunoreactive insulin, and liver function in persons undergoing regularly scheduled health evaluations

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Abstract

Two hundred and thirty eight persons were examined to evaluate the interrelations among seven key factors for arteriosclerosis: body mass index (BMI), systolic blood pressure (BPs), plasma glucose (PG), serum cholesterol (CHO), serum triglyceride (TG), serum glutamic-pyruvic transaminase (SGPT), and serum insulin (IRI). BPs showed the significant positive correlation with PG (r=0.346), BMI (r=0.318), and IRI (r=0.200).However, there were no significant correlations between BPs and CHO, between BPs and TG, between BPs and SGPT. SGPT showed the significant positive correlation with IRI (r=0.367), BMI (r=0.268), and TG (r=0.343); but no significant correlations were observed in relations between SGPT and PG, between SGPT and BPs, between SGPT and CHO. IRI showed the significant positive correlations with TG (r=0.234), and PG (r=0.427). These data suggest that IRI has an effect on BPs and SGPT. The effect of IRI on BPs relates with PG but does not relate with serum lipid. The effect of IRI on SGPT relates with TG but not with PG.

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References

  1. Bray, G.A., Definition, measurement, and classification of the syndromes of obesity.Int. J. Obes. 2:99–112, 1978.

    Google Scholar 

  2. Manicardi, V., Camellini, L., Belloidi, G., Coscelli, C., Ferrannini, E., Evidence for an association of high blood pressure and hyperinsulinemia in obese man.J. Clin. Endo. Metab. 62:1302–1304, 1986.

    Google Scholar 

  3. Reaven, G.M., Role of insulin resistance in human disease.Diabetes 37:1595–1607, 1988.

    Google Scholar 

  4. Yano, K., Reed, D.M., McGee, D.L., Ten-year incidence of coronary heart disease in the Honolulu Heart Program.Am. J. Epidemiol. 119:653–666, 1984.

    Google Scholar 

  5. Carlson, L.A., Bottiger, L.E., Ischemic heart-disease in relation to fasting values of plasma triglycerides and cholesterol.Lancet I:865–868, 1972.

    Google Scholar 

  6. Bhathena, S.J., Avigan, J., Schreiner, M.E., Effect of insulin on sterol and fatty acid synthesis and hydroxymethylglutaryl CoA reductase activity in mammalian cells grown in culture.Proc. Nat. Acad. Sci. 71:2174–2178, 1974.

    Google Scholar 

  7. Devery, R., Tomkin, G.H., The effect of insulin and catecholamines on the activities of 3-hydroxy-3-methyl glutaryl coenzyme A reductase and acyl-coenzyme A: cholesterol-o-acyltransferase in isolated rat hepatocytes.Diabetologia 29:122–124, 1986.

    Google Scholar 

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Nakamura, Y., Katakai, S., Hayakawa, S. et al. Correlative evaluation of serum lipid, blood glucose, blood pressure, serum immunoreactive insulin, and liver function in persons undergoing regularly scheduled health evaluations. J Med Syst 17, 195–199 (1993). https://doi.org/10.1007/BF00996945

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