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An auto-anti-B in an A1B person. Serological studies

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Summary

The serum of a patient (Mr. Lat) with the regular blood group A1B contains an anti-B reacting with all cells having a B antigen except bx and cis AB. The anti-B reacts at 4° C and occasionally at room temperature as shown by agglutination, absorption-elution and by thermo-dynamic assays. The antibody is regarded as an irregular autoantibody belonging to the group of the so called “suppressed” or “latent” antibodies.

Zusammenfassung

Das Serum eines Patienten (Mr. Lat) mit der normalen Blutgruppe A1B enthält Anti-B, das mit allen Zellen reagiert, die ein B-Antigen aufweisen, ausgenommen Bx und cis AB. Das Anti-B reagiert bei 4° C und gelegentlich bei Zimmertemperatur, was durch Agglutination, Absorption-Elution und durch thermodynamische Unter-suchungen gezeigt wurde. Der Antikörper wird als irregulärer Autoantikörper angesehen, der zur Gruppe der „supprimierten“ oder „latenten“ Antikörper gehört.

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Finke, M., Sachs, V., Vollert, B. et al. An auto-anti-B in an A1B person. Serological studies. Blut 32, 371–374 (1976). https://doi.org/10.1007/BF00996477

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  • DOI: https://doi.org/10.1007/BF00996477

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