Skip to main content
Log in

Illness, the mind, and the body: Cancer and immunology: An introduction

  • Published:
Theoretical Medicine Aims and scope Submit manuscript

Abstract

From the sixties on it has become clear how the human physical condition could be influenced by human behavior. Although hypothesis were lacking to understand these connections, nursing research especially proved how systematically introduced patient behavior during illness and hospitalization could induce better recovery results and better prognosis for the patient.Information andattitude proved to be crucial elements in these processes of improved patient expectations. It took less than two decades to get to the insights we have in 1994. Recent research shows the interlocking mechanisms of nervous and endocrine systems with the immune system as significantly being influenced by behavior and especially psychic and or psychosocial stress.

This special issue of Theoretical Medicine briefly describes the historical development with contributions on the most recent state of the scientific art. These developments are emphasized by discussion on the clinical reality of the (breast) cancer patient and recent findings on the complexity of the prevalence of cancer in epidemiology. An attempt is made to consider practical consequences of the actual knowledge if applied to patient care.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Bergsma J, Thomasma DC.Health Care: Its Psychosocial Dimensions. Pittsburgh: Dusquesne Univ. Press, 1982.

    Google Scholar 

  2. Schmitt FE, Wooldridge PJ. Psychological preparation of surgical patients.Nursing Research 1973;2:108–116.

    Google Scholar 

  3. Lindeman CA, Van Aerham B. Nursing intervention with the preoperative teaching.Nursing Research 1971;20:319–332.

    Google Scholar 

  4. Duff RS, Hollingshead AB.Sickness and Society. New York: Harper and Row, 1968.

    Google Scholar 

  5. Sacks O.Awakening. London: Duckworth, 1973.

    Google Scholar 

  6. Gorman JM, Liebowitz MR, Fyer AJ, Stein J. A neuroanatomical hypothesis for panic disorder.Am J Psychiatry 1989;146:2,148–161.

    Google Scholar 

  7. Spiegel D, Bloom JR, Kraemer HC, Gotthel E. Effects of psychosocial treatment on survival of patients with metastatic breast cancer.The Lancet. Oct. 14, 1989:888–891.

    Google Scholar 

  8. Sörensen TIA, Nielsen GC, Andersen PK, Taesdale TW. Genetic and environmental influences on premature death in adult adoptees.New Eng Med 1988;318,12:727–732.

    Google Scholar 

  9. Besedowsky H, Sorkin E. Immunologic-neuroendocrine circuits: psychological approaches. In: Ader R, ed.Psychoneuroimmunology. New York: Academic Press, 1981.

    Google Scholar 

  10. Brown MR, Fisher LA. Corticotropin-releasing factor: effects on the autonomic nervous system and visceral systems.Fed Proc 1985;44:1 243.

    Google Scholar 

  11. Croiset G.The Impact of Emotional Stimuli on the Immune System. Utrecht: Diss. State University, 1989:93.

    Google Scholar 

  12. Ibid::93–94.

    Google Scholar 

  13. Ibid::94.

    Google Scholar 

  14. Ibid::94.

    Google Scholar 

  15. Arhem P, Lindahl BIB. Neuroscience and the problem of consciousness: theoretical and empirical approaches.Theor Med 1993; 1:4:2.

    Google Scholar 

  16. See note 6: Gorman.

    Google Scholar 

  17. Ibid:,158.

    Google Scholar 

  18. Ibid.

    Google Scholar 

  19. Ibid:,148.

    Google Scholar 

  20. Van Rood YR.Stress Induced Changes in Immune Function in Humans. Utrecht: Diss. State Univ. 1992.

    Google Scholar 

  21. Van Rood YR, Bogaards M, Goulmy E, Van Houwelingen HC. The effects of stress and relaxation on the in-vitro immune response in man; a meta-analytic study. Accepted for publication byJ Beh Med (“in press”).

  22. Ibid: 86.

  23. Buske-Kirschbaum A, Kirschbaum C, Stierle H, Lehnert H, Hellhammer D. Conditioned increase of natural killer cell activity (NKCA) in humans.Psychosomatic Med 1992;54:123–132.

    Google Scholar 

  24. Ibid.:130.

    Google Scholar 

  25. Brosschot JF, Benschop RJ, Godaert GLR, De Smet MBM, Olff M, Heynen CJ, Ballieux RE. Effects of experimental psychological stress on distribution and function of peripheral blood cells.Psychosomatic Med 1992;54:394–406. Quote: 403.

    Google Scholar 

  26. Ibid.

    Google Scholar 

  27. Glaser R, Kieholt-Glaser JK, Bonneau RH, Malarkey W, Kennedy S, Hughes J. Stress induced modulation of the immune response to recombinant hepatitis B vaccine.Psychosomatic Med 1992;54:22–29.

    Google Scholar 

  28. Ibid.:22.

    Google Scholar 

  29. Ibid.:27.

    Google Scholar 

  30. Ibid.

    Google Scholar 

  31. See note 8: Sörensen.

    Google Scholar 

  32. Kiecolt-Glaser JK, Dura JS, Speicher CE, Trask OJ, Glaser R. Spousal care-givers of dementia victims: longitudinal changes in immunity and health.Psychosomatic Med 1991;53:345–362.

    Google Scholar 

  33. Ibid::359.

    Google Scholar 

  34. Ibid::359.

    Google Scholar 

  35. Trijsburg RW, Van Knippenberg FCE, Rijpma SE. Effects of psychological treatment on cancer patients: a critical review.Psychosomatic Med 1992;54:489–517.

    Google Scholar 

  36. See note 7: Spiegel.

    Google Scholar 

  37. Ibid::888.

    Google Scholar 

  38. Ibid::889.

    Google Scholar 

  39. Friedman LC, Baer P, Nelson DV, Lane M, Smith E, Dworkin RJ. Women with breast cancer: perception of family functioning and adjustment to illness.Psychosomatic Med 1988;50:529–540.

    Google Scholar 

  40. Levy SM, Herberman RB, Whiteside T, Sanzo K, Lee J, Kikwood J. Perceived social support and tumor estrogen/progesterone receptor status as predictors of natural killer cell activity in breast cancer patients.Psychosomatic Med 1990;52:73–85.

    Google Scholar 

  41. Levy SM, Lee J, Bagley C, Lippman M. Survival hazards analysis in first recurrent breast cancer patients: seven year follow up.Psychosomatic Med 1988;50:520–528. Quote: 526.

    Google Scholar 

  42. Ibid::526.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bergsma, J. Illness, the mind, and the body: Cancer and immunology: An introduction. Theoretical Medicine 15, 337–347 (1994). https://doi.org/10.1007/BF00993792

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00993792

Key words

Navigation