Journal of Chemical Ecology

, Volume 17, Issue 9, pp 1909–1916 | Cite as

Chemical contents of stinging trichomes ofCnidoscolus texanus

  • S. E. Lookadoo
  • A. J. Pollard


Plants known as nettles bear trichomes that deliver a painful sting when touched. Studies of members of the Urticaceae have suggested that their trichomes may contain histamine, acetylcholine, and serotonin. We report investigations using TLC, HPLC, and UV-VIS spectrophotometry to analyze the hair fluids ofCnidoscolus texanus, a member of the Euphorbiaceae, along with standards of known histamine, acetylcholine, and serotonin. Of these, only serotonin was detected in hair extracts. Up to four other compounds were detected and partially characterized, but they have not been identified.

Key Words

Serotonin nettles trichomes stinging hairs plant defense mechanisms Urtica dioica Cnidoscolus texanus 


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  1. Collier, H.O.J., andChesher, G.B. 1956. Identification of 5-hydroxytryptamine in the sting of the nettle (Urtica dioica).Br. J. Pharmacol. 11:186–189.Google Scholar
  2. Cordeiro, R., Aragao, J., andMorhy, L. 1983. The presence of histamine inCnidosculus [sic]oligandrus (Euphorbiaceae).An. Acad. Brasil. Cienc. 55:123–128.Google Scholar
  3. Emmelin, N., andFeldberg, W. 1947. The mechanism of the sting of the common nettle (Urtica dioica).J. Physiol. 106:440–445.Google Scholar
  4. Emmelin, N., andFeldberg, W. 1949. Distribution of acetylcholine and histamine in nettle plants.New Phytol. 48:143–148.Google Scholar
  5. Flury, F. 1927. Uber die chemische Natur der Nesselgifte.Z. Gesamte Exp. Med. 56:402–409.Google Scholar
  6. Lutz, D. 1914. The poisonous nature of the stinging hairs ofJatropha [=Cnidoscolus]urens.Science 40:609–610.Google Scholar
  7. MacFarlane, W.V. 1963. The stinging properties of Laportea.Econ. Bot. 17:303–311.Google Scholar
  8. Oelrichs, P.B., andRobertson, P.A. 1970. Purification of pain-producing substances fromDendrocnide (Laportea) moroides.Toxicon 8:89–90.Google Scholar
  9. Pollard, A.J. 1986. Variation inCnidoscolus texanus in relation to herbivory.Oecologia 70:411–413.Google Scholar
  10. Pollard, A.J., andBriggs, D. 1984. Genecological studies ofUrtica dioica L. III. Stinging hairs and plant-herbivore interactions.New Phytol. 97:507–522.Google Scholar
  11. Robertson, P.A., andMacFarlane, W.V. 1957. Pain-producing substances from the stinging bushLaportea moroides.Aust. J. Exp. Biol. Med. Sci. 35:381–393.Google Scholar
  12. Thurston, E.L. 1974. Morphology, fine structure, and ontogeny of the stinging emergence ofUrtica dioica.Am. J. Bot. 61:809–817.Google Scholar
  13. Thurston, E.L., andLersten, N.R. 1969. The morphology and toxicology of plant stinging hairs.Bot. Rev. 35:393–412.Google Scholar
  14. Willis, C.L. 1969. Toxic constituents of the stinging nettle. M.S. thesis. Iowa State University, Ames, Iowa.Google Scholar
  15. Winkler, H. 1922. Die Urticaceen Papuasiens.Bot. Jahrb. 57:501–608.Google Scholar

Copyright information

© Plenum Publishing Corporation 1991

Authors and Affiliations

  • S. E. Lookadoo
    • 1
  • A. J. Pollard
    • 1
  1. 1.Department of BiologyFurman UniversityGreenville

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