Conclusions
The isolation of hnRNP complexes has identified many new proteins and their characterization has led to the identification of several motifs that are important for RNA binding. These motifs are present in a wide variety of proteins including splicing factors, ribosomal proteins, and several proteins of unknown function. These findings have blurred the lines of demarcation between proteins previously thought of as RNA “packaging” proteins and RNA processing factors. Recent findings on hnRNP proteins have suggested a plethora of possible functions along the pathway of mRNA metabolism. It can be expected that the next few years will see the unraveling of the detailed functions of hnRNP proteins.
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Görlach, M., Burd, C.G., Portman, D.S. et al. The hnRNP proteins. Mol Biol Rep 18, 73–78 (1993). https://doi.org/10.1007/BF00986759
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DOI: https://doi.org/10.1007/BF00986759