Pediatric Radiology

, Volume 13, Issue 5, pp 266–268 | Cite as

Lower extremity deep vein thrombosis in children

  • L. Perlmutt
  • K. E. Fellows


Of 113 leg venograms performed in patients of all ages between 1969 and 1982, 68 were in children 16 years old or less. The patients were all studied on a tilt table (method of Rabinov and Paulin) in a head-up, 40–50° incline without tourniquets, supporting their weight on the unaffected leg. Among the 68 venograms, 12 (18%) were positive for deep vein thrombosis. The clinical settings for thrombosis in children were post-catheterization (two patients), post surgery (two), tumor/tumor therapy (three), drug abuse (one), infection (one), and idiopathic (three). There were no long-term clinical sequelae in five patients. Pulmonary infarction occurred in three, and three patients required either long-term anticoagulation or IVC clipping. Clinical diagnosis is no more accurate for the diagnosis of deep vein thrombosis in children than it is in adults. Venography is the best method for making an accurate diagnosis and directing subsequent therapy.

Key Words

Venogram Lower extremity deep vein thrombosis 


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  1. 1.
    Wise RC, Todd JK (1973) Spontaneous, lower — extremity venous thrombosis in children. Am J Dis Child 126: 766PubMedGoogle Scholar
  2. 2.
    Jones DRB, Macintyre IMC (1975) Venous thromboembolism in infancy and childhood. Arch Dis Child 50: 153PubMedGoogle Scholar
  3. 3.
    Blabey RG, Weil R, Santulli TV (1975) Ileofemoral thrombophlebitis associated with central nervous system pathology. Am J Surg 130 (3): 315PubMedGoogle Scholar
  4. 4.
    Horwitz J, Shenker R (1977) Spontaneous deep vein thrombosis in adolescence. Clin Pediatr 16: 787Google Scholar
  5. 5.
    Nachbur B, Baumgartner G, Huser HJ (1979) Deep thrombophlebitis of the lower extremities in children. Vasa 8: 53PubMedGoogle Scholar
  6. 6.
    Rabinov K, Paulin S (1972) Roentgen diagnosis of venous thrombosis in the leg. Arch Surg 104: 134PubMedGoogle Scholar
  7. 7.
    Bettmann MA, Paulin S (1977) Leg phlebography: the incidence, nature, and modification of undesirable side effects. Radiology 122: 101PubMedGoogle Scholar
  8. 8.
    Kakkar VV (1977) Fibrinogen uptake test for detection of deep vein thrombosis — a review of current practice. Semin Nucl Med 7: 229PubMedGoogle Scholar
  9. 9.
    Coon W, Collier F (1959) Clinicopathologic correlation in thromboembolism. Surg Gynecol Obstet 109: 259PubMedGoogle Scholar
  10. 10.
    Nicolaides AN (1978) Diagnosis of venous thrombosis by phlebography. In: Bergan JJ, Yad JST (eds) Venous problems. Year Book Medical Publishers, Chicago, p 123Google Scholar
  11. 11.
    Nissl R (1979) Acute thrombosis. In: May R (ed) Surgery of the veins of the leg and pelvis. WB Saunders, Philadelphia, p 96Google Scholar
  12. 12.
    Welch CE, Faxon HH (1941) Thrombophlebitis and pulmonary embolism. JAMA 117: 1502Google Scholar
  13. 13.
    Hull R, Van Acken WG (1976) Impedence plethysmography using the occlusive cuff technique in the diagnosis is of venous thrombosis. Circulation 52: 696Google Scholar
  14. 14.
    Williams WJ (1973) Venography. Circulation 47: 270PubMedGoogle Scholar
  15. 15.
    Porter J, Jick H (1977) Drug-related deaths among medical inpatients. JAMA 237: 879PubMedGoogle Scholar
  16. 16.
    Shapiro S, Slone D, Lewis GP, Jick H (1971) Fatal drug reactions among medical inpatients. JAMA 216: 467PubMedGoogle Scholar
  17. 17.
    Armstrong B, Dinan B, Jick H (1976) Fatal drug reactions in patients admitted to surgical services. Am J Surg 132: 643PubMedGoogle Scholar

Copyright information

© Springer-Verlag 1983

Authors and Affiliations

  • L. Perlmutt
    • 1
    • 2
  • K. E. Fellows
    • 1
    • 3
  1. 1.Department of RadiologyHarvard Medical SchoolBostonUSA
  2. 2.Brigham and Women's HospitalBostonUSA
  3. 3.Children's Hospital Medical CenterBostonUSA

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