Neurochemical Research

, Volume 13, Issue 7, pp 633–635 | Cite as

Lack of physiological stimulation induces decreased proteolytic activity in nerve terminals

  • S. Gustavsson
  • J. -O. Karlsson
Original Articles


The effect of optic nerve transsection on proteolytic degradation of axonally transported proteins in the superior colliculus of the rabbit was studied. Proteolysis of labeled proteins was determined in vitro in small pieces of the superior colliculus. Within 2 hours after sectioning the optic nerve there was a decreased degradation of slowly transported labeled proteins in the nerve terminals in the superior colliculus.

Key Words

Nerve activity proteolysis 


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Copyright information

© Plenum Publishing Corporation 1988

Authors and Affiliations

  • S. Gustavsson
    • 1
  • J. -O. Karlsson
    • 1
  1. 1.Institue of NeurobiologyUniversity of GöteborgGöteborgSweden

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