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Lateral differences in GABA binding sites in rat brain

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Abstract

An asymmetric distribution of GABA binding sites was found in the cerebral cortex, hippocampus, cerebellar hemispheres, striatum, and thalamus. Higher levels of [3H]GABA binding were observed in the left-side of most brain areas and in a greater percentage of adult rats, but the opposite asymmetry was found in the thalamus. A similar left-right difference in cerebral hemispheres was also found in five day-old rats, suggesting the genetic predetermination of asymmetry.

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Guarneri, P., Guarneri, R., La Bella, V. et al. Lateral differences in GABA binding sites in rat brain. Neurochem Res 13, 209–211 (1988). https://doi.org/10.1007/BF00971534

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