Neurochemical Research

, Volume 8, Issue 9, pp 1185–1195 | Cite as

Effects of base exchange reaction on the Na+, K+ ATPase in rat brain microsomes

  • Hiroshi Hattori
  • Julian N. Kanfer
Original Articles


Incorporation of ethanolamine and monomethylethanolamine into their corresponding phospholipid by the base exchange enzymes activated an Na+, K+-ATPase associated with a rat brain microsomes enriched preparation. The serine and dimethylethanolamine base exchange catalyzed incorporation reactions inhibited this particular Na+, K+-ATPase. These effects require Ca+ and several other structural analogues which are not incorporated into phospholipid were without affect on this ATPase.


Serine Exchange Reaction Ethanolamine Structural Analogue Base Exchange 
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Copyright information

© Plenum Publishing Corporation 1983

Authors and Affiliations

  • Hiroshi Hattori
    • 1
  • Julian N. Kanfer
    • 1
  1. 1.Department of Biochemistry Faculty of MedicineThe University of ManitobaManitoba

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