Advertisement

Neurochemical Research

, Volume 1, Issue 5, pp 501–509 | Cite as

Arylalkylamines inOctopus tissues

  • A. V. Juorio
  • S. R. Philips
Article

Abstract

A number of phenylethylamines and indoleamines have been analyzed in the circumoesophageal ganglia and posterior salivary gland of the normal and pargyline-treated maleOctopus dofleini martini. β-Phenylethylamine,m-tyramine, and tryptamine are present in the optic lobes in amounts of 3, 0.6, and 0.6 ng/g, and in the posterior salivary gland at levels of 1, 64, and 52 ng/g, respectively, in contrast to the much higher levels observed forp-tyramine, octopamine, dopamine, noradrenaline, and 5-hydroxytryptamine. Although pargyline causes a substantial increase in the content of β-phenylethylamine,m-tyramine,p-tyramine, and tryptamine in the optic lobes, no significant changes are observed in the posterior salivary gland. Their relatively rapid metabolism suggests an active role for these amines in the function of nervous tissue in theOctopus.

Keywords

Dopamine Noradrenaline Salivary Gland Active Role Nervous Tissue 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Barlow, J.J., Juorio, A.V., andMartin, R. (1974) Monoamine transport in theOctopus posterior salivary gland nerves. J. Comp. Physiol. 89, 105–122.Google Scholar
  2. 2.
    Blaschko, H., andHawkins, J. (1952) Observation on amine oxidase in cephalopods. J. Physiol. London 118, 88–93.PubMedGoogle Scholar
  3. 3.
    Bogdanski, D.F., Pletscher, A., Brodie, B.B., andUdenfriend, S. (1956) Identification and assay of serotonin in brain. J. Pharmacol. Exp. Ther. 117, 82–88.PubMedGoogle Scholar
  4. 4.
    Boulton, A.A., Juorio, A.V., Philips, S.R., andWu P.H. (1975) Some arylalkylamines in rabbit brain. Brain Res. 96, 212–216.PubMedGoogle Scholar
  5. 5.
    Durden, D.A., Philips, S.R., andBoulton, A.A., (1973) Identification and distribution of β-phenylethylamine in the rat. Can. J. Biochem. 51, 995–1002.Google Scholar
  6. 6.
    Erspamer V. (1948) Active substances in the posterior salivary glands of octopoda. I. Enteramine-like substance. Acta Pharmacol. Toxicol. 4, 213–223.Google Scholar
  7. 7.
    Erspamer, V. (1948) Active substances in the posterior salivary glands of octopoda. II. Tyramine and octopamine. Acta Pharmacol. Toxicol. 4, 224–227.Google Scholar
  8. 8.
    Euler, U.S.V. (1953) Presence of catecholamines in visceral organs of fish and invertebrates. Acta Physiol. Scand. 28, 297–305.PubMedGoogle Scholar
  9. 9.
    Henze, M. (1913)p-Oxyphenylathylämin, das Speicheldrüsengift der Cephalopoden. Hoppe-Seyler's Z. Physiol. Chem. 87, 51–58.Google Scholar
  10. 10.
    Juorio, A.V. (1971) Catecholamines and 5-hydroxytryptamine in nervous tissue of cephalopods. J. Physiol. London 216, 213–226.PubMedGoogle Scholar
  11. 11.
    Juorio, A.V., andKillick, S.W. (1972) Monoamines and their metabolism in molluscs. Comp. Gen. Pharmacol. 3, 283–295.PubMedGoogle Scholar
  12. 12.
    Juorio, A.V., andKillick, S.W. (1972) The effects of drugs on the synthesis and storage of monoamines in nervous tissues of molluscs. Int. J. Neurosci. 4, 195–202.Google Scholar
  13. 13.
    Juorio, A.V. andKillick, S.W., (1973) The distribution of monoamines and some of their acid metabolites in the posterior salivary glands and viscera of some cephalopods. Comp. Biochem. Physiol. 44A, 1059–1067.Google Scholar
  14. 14.
    Juorio, A.V., andMolinoff, P.B. (1974) The normal occurrence of octopamine in neural tissues of theOctopus and other cephalopods. J. Neurochem. 22, 271–280.PubMedGoogle Scholar
  15. 15.
    Juorio, A.V. andPhilips, S.R. (1975) Tyramines inOctopus nerves. Brain Res. 83, 180–184.Google Scholar
  16. 16.
    Laverty, R., andSharman, D.F. (1965) The estimation of small quantities of 3,4-dihydroxyphenylethylamine in tissue. Br. J. Pharmacol. 24, 538–548.PubMedGoogle Scholar
  17. 17.
    Molinoff, P.B., andAxelrod, J. (1969) Octopamine: Normal occurrence in sympathetic nerves of rats. Science 164, 428, 429.PubMedGoogle Scholar
  18. 18.
    Philips, S.R., Davis, B.A., Durden, D.A., andBoulton, A.A. (1975) Identification and distribution of meta-tyramine in the rat. Can. J. Biochem. 53, 65–69.PubMedGoogle Scholar
  19. 19.
    Philips, S.R., Durden, D.A., andBoulton, A.A. (1974) Identification and distribution ofp-tyramine in the rat. Can. J. Biochem. 52, 366–373.PubMedGoogle Scholar
  20. 20.
    Philips, S.R., Durden, D.A., andBoulton, A.A. (1974) Identification and distribution of tryptamine in the rat. Can. J. Biochem. 52, 447–451.Google Scholar
  21. 21.
    Robertson, H.A., andJuorio, A.V. (1977) Octopamine and some related noncatecholic amines in invertebrate nervous systems. Int. Rev. Neurobiol. 19, 173–224.Google Scholar
  22. 22.
    Saavedra, J.M. (1974) Enzymatic isotopic method for octopamine at the picogram level. Anal. Biochem. 59, 628–633.PubMedGoogle Scholar
  23. 23.
    Usdin, E., andSandler, M. (eds.) (1976) Trace Amines and the Brain, M. Dekker, New York.Google Scholar

Copyright information

© Plenum Publishing Corporation 1976

Authors and Affiliations

  • A. V. Juorio
    • 1
  • S. R. Philips
    • 1
  1. 1.Psychiatric Research DivisionUniversity HospitalSaskatoonCanada

Personalised recommendations