Movement-related cortical potentials during handgrip contractions with special reference to force and electromyogram bilateral deficit

  • Shingo Oda
  • Toshio Moritani
Original Article


We investigated movement-related cortical potentials from motor cortex areas (C3 and C4) and isometric force and electromyogram (EMG) activity in association with maximal bilateral (BL) and unilateral (UL) handgrip contraction in eight right-handed subjects. The BL grip exhibited deficits in force [right, −5.2 (SEM 1.1)%; left, −4.5 (SEM 1.9)%] and EMG [right, −9.5 (SEM 2.2)%; left, −7.6 (SEM 2.5)%] compared with the UL grip. In the UL contractions, the amplitudes of the negative slope [NS′ 2.77 (SEM 0.70) vs 2.40 (SEM 0.76) μV·s for left hand,P < 0.05; 2.54 (SEM 0.55) vs 2.23(SEM 0.54) μV·s for right hand,P < 0.05 and motor potentials [MP: 1.56 (SEM 0.32) μV.s vs 1.23 (SEM 0.35) μV·s for left hand,P < 0.01; 1.44 (SEM 0.32) μV·s vs 1.10 (SEM 0.25) μV·s for right hand,P < 0.01] were greater in the contralateral hemisphere. For the BL contractions, the asymmetry of the larger potentials for the contralateral side disappeared and lower symmetrical potentials [NS′, 2.43 (SEM 0.61) μV·s for C3 vs 2.43 (SEM 0.63) μV·s for C4: MP: 1.31 (SEM 0.35) μV·s for C3 vs 1.34 (SEM 0.32) μV·s for C4] were observed. It was concluded that the BL deficit in force and EMG is associated with reduced movement-related cortical potentials suggesting that the bilateral force and (EMG) deficit compared with unilateral hand-grip contractions is caused by a mechanism of interhemispheric inhibition.

Key words

Movement-related cortical potentials Maximal contraction Bilateral deficit 


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  1. Asanuma H, Okuda O (1962) Effects of transcallosal volleys on pyramidal tract cell activity of cat. J Neurophysiol 25:198–208Google Scholar
  2. Barrett G, Shibasaki H, Neshige R (1986) Cortical potentials preceding voluntary movement: Evidence for three periods of preparation in man. Electroenceph Clin Neurophysiol 63:327–339Google Scholar
  3. Deecke L, Scheid P, Kornhuber HH (1969) Distribution of readiness potentials, pre-motion positivity and motor potential of the human cerebral cortex preceding voluntary finger movements. Exp Brain Res 7:158–168Google Scholar
  4. Ferbert A, Priori A, Rothwell JC, Day BL, Colebatch JG, Marsden CD (1992) Interhemispheric inhibition of the human motor cortex. J. Physiol 453:525–546Google Scholar
  5. Gemba H, Sasaki K, Hashimoto S (1980) Distribution premovement slow cortical potentials associated with self-paced hand movements in monkeys. Neurosci Lett 20:159–163Google Scholar
  6. Gerbrandt LK, Goff WR, Smith DB (1973) Distribution of the human average movement potential. Electroenceph Clin Neurophysiol 34:461–474Google Scholar
  7. Gould HJ, Cusick CG, Pons TP, Kaas JH (1986) The relationship of corpus callosum connection to electrical stimulation maps of motor, supplementary motor, and the frontal eye fields in owl monkeys. J. Comp Neurol 247:297–325Google Scholar
  8. Hashimoto S, Gemba H, Sasaki K (1979) Analysis of slow cortical potentials self-paced hand movements in the monkey. Exp Neurol 65:218–229Google Scholar
  9. Henry FM, Smith LE (1961) Simultaneous vs. separate bilateral muscular contractions in relation to neural overflow theory and neuromoter specificity. Res Quart 32:42–46Google Scholar
  10. Jenny JB, (1979) Commissural projections of the cortical hand motor area in monkeys. J Comp Neurol 188:137–146Google Scholar
  11. Koh TJ, Grabiner MD, Clough CA (1993) Bilateral deficit is larger for step than for ramp isometric contractions. J. Appl Physiol 74:1200–1205Google Scholar
  12. Kristeva R, Keller E, Deecke L, Kornhuber HH (1979) Cerebral potential preceding unilateral and simultaneous bilateral finger movements. Electroenceph Clin Neurophysiol 47:229–238Google Scholar
  13. Kristeva R, Cheyne D, Lang W, Lindinger G, Deecke L (1990) Movement-related potentials accompanying unilateral and bilateral finger movements with different initial loads. Electroenceph Clin Neurophysiol 75:410–418Google Scholar
  14. Kristeva R, Cheyne D, Deecke L (1991) Neuromagnetic fields accompanying unilateral and bilateral voluntary movements: topography and analysis of cortical sources. Electroenceph Clin Neurophysiol 81:284–298Google Scholar
  15. Kroll W (1965) Isometric cross-transfer effects under conditions of central facilitation. J Appl Physiol 20:297–300Google Scholar
  16. Neshige R, Luders H, Shibasaki H (1988) Recording of movementrelated cortical potentials from scalp and cortex in man. Brain 111:719–736Google Scholar
  17. Oda S, Moritani T (1994) Maximal isometric force and neural activity during bilateral and unilateral elbow flexion in humans. Eur J Appl Physiol 69:240–243Google Scholar
  18. Ohtsuki T (1981) Decrease in grip strength induced by simultaneous bilateral exertion with reference to finger strength. Ergonomics 24:37–48Google Scholar
  19. Ohtsuki T (1983) Decrease in human voluntary isometric arm strength induced by simultaneous bilateral exertion. Behav Brain Res 7:165–178Google Scholar
  20. Pappas CL, Strick PL (1981) Anatomical demonstration of multiple representation in the forelimb region of the cat motor cortex. J Comp Neurol 200:491–500Google Scholar
  21. Rektor I, Fève A, Buser P, Bathien N, Lamarche M (1994) Intracerebral recording of movement related readiness potentials: an exploration in epileptic patients. Electroenceph Clin Neurophysiol 90:273–283Google Scholar
  22. Rothwell JC, Colebatch JG, Britton TC, Priori A, Thompson PD, Day BL, Marsden CD (1991) Physiological studies in a patient with mirror movements and agenesis of the corpus callosum. J Physiol 438:34PGoogle Scholar
  23. Secher NH, Rørsgaard S, Secher O (1978) Contralateralinfluence on recruitment of curarized muscle fibres during maximal voluntary extension of the legs. Acta Physiol Scand 103:456–462Google Scholar
  24. Secher NH, Rube N, Elers J (1988) Strength of two- and one-leg extension in man. Acta Physiol Scand 134:333–339Google Scholar
  25. Shibasaki H, Kato M (1975) Movement-associated cortical potentials with unilateral and bilateral simultaneous hand movement. J. Neurol 208:191–199Google Scholar
  26. Shibasaki H, Barrett G, Halliday E, Halliday AM (1980) Components of the movement-related cortical potential and the scalp topography. Electroenceph Clin 49:213–226Google Scholar
  27. Shibasaki H, Barrett G, Halliday E, Halliday AM (1981) Cortical potentials associated with voluntary foot movement in man. Electroenceph Clin Neurophysiol 52:507–516Google Scholar
  28. Singh J, Knight RT (1990) Frontal lobe contribution to voluntary movements in humans, Brain Res 531:45–54Google Scholar
  29. Taylor MG (1978) Bereitschaftspotential during the acquisition of a skilled motor task. Electroenceph Clin Neurophysiol 45:568–576Google Scholar
  30. Vandervoot AA, Sale DG, Moroz J (1984) Comparison of motor unit activation during unilateral and bilateral leg extension. J Appl Physiol 56:46–51Google Scholar
  31. Wyke M (1969) Influence of direction on the rapidity of bilateral arm movements. Neurophychologia 7:189–194Google Scholar

Copyright information

© Springer-Verlag 1995

Authors and Affiliations

  • Shingo Oda
    • 1
  • Toshio Moritani
    • 2
  1. 1.Laboratory of Motor Control, Faculty of Integrated Human StudiesKyoto UniversitySakyo-ku, KyotoJapan
  2. 2.Laboratory of Applied Physiology, Graduate School of Human and Environmental StudiesKyoto UniversitySakyo-ku, KyotoJapan

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