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Neurochemical Research

, Volume 9, Issue 3, pp 325–331 | Cite as

Lesion-induced catecholaminergic sprouting in the interpeduncular nucleus

  • Zehava Gottesfeld
Original Articles

Abstract

This work examined the capacity of intact catecholaminergic axon terminals to sprout in the partially deafferented interpeduncular nucleus (IPN). The results show that norepinephrine and dopamine levels were markedly increased in the IPN 6 weeks after bilateral habenula (Hb) lesions. These changes were accompanied by intensified fluorescence of sprouting axon terminals, as demonstrated by fluorescent histochemistry. The results suggest that both noradrenergic (NA) and dopaminergic neuronal systems respond concomitantly to removal of converging but heterogeneous input to the IPN.

Keywords

Dopamine Norepinephrine Axon Terminal Neuronal System Dopamine Level 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1984

Authors and Affiliations

  • Zehava Gottesfeld
    • 1
  1. 1.Department of Neurobiology and AnatomyUniversity of Texas Medical School at HoustonHouston

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