Neurochemical Research

, Volume 4, Issue 3, pp 331–337 | Cite as

Glycoprotein galactosyltransferase activity in synaptic junctional complexes isolated from rat forebrain

  • Jeffry F. Goodrum
  • H. B. Bosmann
  • Ryo Tanaka
Original Articles

Abstract

A synaptosomal plasma membrane fraction and its junctional and nonjunctional subfractions were isolated and analyzed for glycoprotein galactosyltransferase activity. The nonjunctional components fraction had the highest specific activity in the presence of exogenous acceptor, suggesting an enrichment of enzyme in this fraction. The synaptic junctional complex fraction had the highest specific activity in the absence of added acceptor, suggesting that there is a relative enrichment of endogenous acceptors for this galactosyltransferase within the synaptic junctional complex.

Keywords

Plasma Membrane Membrane Fraction High Specific Activity Junctional Complex Complex Fraction 

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Copyright information

© Plenum Publishing Corporation 1979

Authors and Affiliations

  • Jeffry F. Goodrum
    • 1
  • H. B. Bosmann
    • 1
  • Ryo Tanaka
    • 1
  1. 1.Center for Brain Research, Department of Pharmacology and Toxicology and the University of Rochester Cancer CenterUniversity of Rochester School of Medicine and DentistryRochester

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