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Substituted ethynylphosphonates and their anticholinesterase activity

  • Organic Chemistry
  • Published:
Bulletin of the Academy of Sciences of the USSR, Division of chemical science Aims and scope

Conclusions

  1. 1.

    A series of substituted ethynylphosphonates was synthesized, and their anticholinesterase activity was studied.

  2. 2.

    The investigated compounds can inhibit cholinesterase of various origins irreversibly.

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Literature cited

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Authors and Affiliations

  1. A. N. Nesmeyanov Institute of Heteroorganic Compounds, Academy of Sciences of the USSR, Moscow

    A. P. Brestkin, L. A. Vikhreva, N. N. Godovikov, V. S. Gorbatyuk, S. N. Moralev & M. I. Kabachnik

Authors
  1. A. P. Brestkin
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  2. L. A. Vikhreva
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  3. N. N. Godovikov
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  4. V. S. Gorbatyuk
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  5. S. N. Moralev
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  6. M. I. Kabachnik
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Additional information

Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 9, pp. 2118–2123, September, 1988.

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Brestkin, A.P., Vikhreva, L.A., Godovikov, N.N. et al. Substituted ethynylphosphonates and their anticholinesterase activity. Russ Chem Bull 37, 1900–1905 (1988). https://doi.org/10.1007/BF00962510

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  • DOI: https://doi.org/10.1007/BF00962510

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