Reaction of phosphorus-containing cyanoguanidines with hexafluoroacetone imines
- 26 Downloads
Substituted hexafluoroacetone imines react with 1-(2-cyanoguanidino) alkylphosphonates at the C≡N group at −5-0°C, forming [2+4]-cycloaddition products, which are phosphorus-containing 4,4-bis(trifluoromethyl)1,3,5-oxadiazines. The reaction products are readily alkylated by substituted hexafluoroacetone imines at the nitrogen atom of the guanidine fragment. The two reactions are accompanied by tautomeric transformations of the guanidine fragment of the molecules. An NMR spectral analysis was carried out.
KeywordsNitrogen Nitrogen Atom Spectral Analysis Guanidine Trifluoromethyl
Unable to display preview. Download preview PDF.
- 1.V. B. Sokolov, A. Yu. Aksinenko, and O. V. Korenchenko, Summaries of Lectures at the 9th Conference of Young Scientists on “Synthesis and Investigation of Biologically Active Compounds” [inRussian], Riga (1987), p. 15.Google Scholar
- 2.I. V. Fokin, A. F. Kolomiets, and N. V. Vasil'ev, Usp. Khim.,53, 398 (1984).Google Scholar
- 3.I. V. Martynov, A. N. Chekhlov, A. Yu. Aksinenko, et al., Zh. Obshch. Khim.,57, 2285 (1987).Google Scholar