S-S exchange of cysteine-containing peptides in different methods of mass spectrometric analysis

  • O. S. Reshetova
  • B. V. Rozynov
  • I. A. Bogdanova
  • V. G. Merimson
  • V. M. Kondrat'ev
  • G. V. Fridlyanskii
  • V. A. Nikolaev
  • A. L. Zhuze
Physical Chemistry
  • 23 Downloads

Conclusions

  1. 1.

    Mass spectra of five cysteine-containing peptides and their mixtures were obtained by mass spectrometry methods under the conditions of electron impact, chemical ionization, field desorption bombardment by accelerated electrons and extraction of ions from solution under atmospheric pressure.

     
  2. 2.

    It was found that under ESIAP conditions, the cysteine-containing peptides do not undergo the S-S exchange observed in their investigation by other ionization methods.

     

Keywords

Peptide Mass Spectrometry Mass Spectrum Electron Impact Chemical Ionization 

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Copyright information

© Plenum Publishing Corporation 1988

Authors and Affiliations

  • O. S. Reshetova
    • 1
    • 2
    • 3
  • B. V. Rozynov
    • 1
    • 2
    • 3
  • I. A. Bogdanova
    • 1
    • 2
    • 3
  • V. G. Merimson
    • 1
    • 2
    • 3
  • V. M. Kondrat'ev
    • 1
    • 2
    • 3
  • G. V. Fridlyanskii
    • 1
    • 2
    • 3
  • V. A. Nikolaev
    • 1
    • 2
    • 3
  • A. L. Zhuze
    • 1
    • 2
    • 3
  1. 1.M. M. Shemyakin Institute of Bioorganic ChemistryAcademy of Sciences of the USSRMoscow
  2. 2.Institute of Analytical Instruments EngineeringAcademy of Sciences of the USSRLeningrad
  3. 3.Institute of Molecular BiologyAcademy of Sciences of the USSRMoscow

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