Abstract
The bromination of phenylisoxazoles in 85% acetic acid is a second-order reaction. The ratios of the rate constants for the bromination of benzene and the investigated compounds are 1∶100–10,000. The maximum reaction rate was observed when a twofold excess of the heterocycles was present, and this constitutes evidence for the intermediate formation of complexes of isoxazoles with bromine.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literature cited
S. D. Sokolov, T. N. Egorova, and P. V. Petrovskii, Khim. Geterotsikl. Soedin., 602 (1974).
N. K. Kochetkov, S. D. Sokolov, and N. M. Vagurtova, Zh. Obshch. Khim.,31, 2326 (1961).
S. D. Sokolov and I. M. Yudintseva, Khim. Geterotsikl. Soedin., 1325 (1973).
E. Berliner and J. C. Powers, J. Amer. Chem. Soc.,83, 905 (1961).
E. Berliner and F. Gaskin, J. Org. Chem.,32, 1660 (1967).
E. Berliner and M. C. Beckett, J. Amer. Chem. Soc.,79, 1425 (1957).
L. Altschuler and E. Berliner, J. Amer. Chem. Soc.,88, 5837 (1966).
Author information
Authors and Affiliations
Additional information
See [1] for communication XXIX.
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 6, pp. 742–744, June, 1975.
Rights and permissions
About this article
Cite this article
Sokolov, S.D., Yudintseva, I.M. Research in the isoxazole series. Chem Heterocycl Compd 11, 643–645 (1975). https://doi.org/10.1007/BF00959950
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00959950