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Simple and direct synthesis of N,N′-disuccinimidyl sulfite

  • Organic Chemistry
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Bulletin of the Academy of Sciences of the USSR, Division of chemical science Aims and scope

Conclusions

A method has been developed for the synthesis of N,N′-disuccinimidyl sulfite, a highly effective reagent for peptide synthesis, via the reaction of N-hydroxysuccinimide with thionyl chloride in the presence of an organic base.

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Literature cited

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Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 11, pp. 2579–2580, November, 1988.

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Il'ina, A.V., Davidovich, Y.A. & Rogozhin, S.V. Simple and direct synthesis of N,N′-disuccinimidyl sulfite. Russ Chem Bull 37, 2326–2327 (1988). https://doi.org/10.1007/BF00959888

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  • DOI: https://doi.org/10.1007/BF00959888

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