X-ray structural and13C NMR spectroscopic investigation of 4,7-diaminocoumarins

  • D. S. Yufit
  • M. A. Kirpichenok
  • Yu. T. Struchkov
  • L. A. Karandashova
  • I. I. Grandberg
Physical Chemistry

Abstract

An x-ray structural study has been made of 7-diethylaminocoumarin and 4-morpholino-7-diethylaminocoumarin. A study has been made of the13C NMR spectra of these compounds and other 4,7-diaminocoumarins, in CDCl3, and in acidic media. These studies have established that the site of first protonation is the nitrogen atom in position 7, and the site of the second protonation is the lactone oxygen atom. It is concluded that the 4-amino group is effectively conjugated with the carbonyl group in 4,7-diaminocoumarins.

Keywords

Oxygen Nitrogen CDCl3 Carbonyl Oxygen Atom 

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Copyright information

© Plenum Publishing Corporation 1991

Authors and Affiliations

  • D. S. Yufit
    • 1
  • M. A. Kirpichenok
    • 1
  • Yu. T. Struchkov
    • 1
  • L. A. Karandashova
    • 1
  • I. I. Grandberg
    • 1
  1. 1.A. N. Nesmeyanov Institute of Heteroorganic CompoundsAcademy of Sciences of the USSRMoscow

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