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Synthesis of bicyclic Β-oxo nitrones: Derivatives of 6-azabicyclo[3.2.1] octane and their reactions with nucleophilic reagents

  • V. A. Reznikov
  • I. A. Urzhuntseva
  • L. B. Volodarskii
Organic Chemistry
  • 28 Downloads

Abstract

It was shown that the recyclization of enamino ketones (hydrogenated derivatives of benzimidazole), which proceeds in an acid medium, leads to 6-azabicyclo[3.2.1]-oct-6-en-8-ones. The reactions of these with nucleophilic reagents proceed primarily at the carbonyl group, while reactions with an excess of organometallic reagents with subsequent oxidation lead to stable nitroxide radicals (derivatives of 6-azabicyclo[3.2.1]octane).

Keywords

Oxidation Carbonyl Ketone Carbonyl Group Acid Medium 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Publishing Corporation 1991

Authors and Affiliations

  • V. A. Reznikov
    • 1
  • I. A. Urzhuntseva
    • 1
  • L. B. Volodarskii
    • 1
  1. 1.Novosibirsk Institute of Organic Chemistry, Siberian BranchAcademy of Sciences of the USSRUSSR

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