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A mathematical model for the methoxycarbonylation of acetylenic alcohols in the presence of the PdCl2-CuCl2-NaOAc system

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Bulletin of the Academy of Sciences of the USSR, Division of chemical science Aims and scope

Conclusion

  1. 1.

    Mathematical planning was used to study the reaction of 3-methyl-l-butyn-3-o1 with carbon monoxide in methanol in the presence of the PdCl2-CuCl2-NaOAc catalytic system, leading to the methyl ester of 4-methyl-4-hydroxy-2-pentynoic acid and equations were obtained describing the effect of the reaction conditions on the yield of this product in the range of variation selected for the major factors.

  2. 2.

    The mathematical model was used to show that the yield of the product may be raised by increasing the concentration of CuCl2 and NaOAc with concurrent decrease in the relative amount of the palladium component of this catalyst.

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Authors and Affiliations

  1. Irkutsk Institute of Organic Chemistry, Siberian Branch, Academy of Sciences of the USSR, USSR

    B. A. Trofimov, A. I. Gritsa, S. N. Istomina, A. G. Mal'kina & Yu. M. Skvortsov

Authors
  1. B. A. Trofimov
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  2. A. I. Gritsa
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  3. S. N. Istomina
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  4. A. G. Mal'kina
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  5. Yu. M. Skvortsov
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Additional information

Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 10, pp. 2336–2339, October, 1986.

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Trofimov, B.A., Gritsa, A.I., Istomina, S.N. et al. A mathematical model for the methoxycarbonylation of acetylenic alcohols in the presence of the PdCl2-CuCl2-NaOAc system. Russ Chem Bull 35, 2139–2142 (1986). https://doi.org/10.1007/BF00957545

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  • DOI: https://doi.org/10.1007/BF00957545

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