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Chemistry of Heterocyclic Compounds

, Volume 5, Issue 5, pp 681–682 | Cite as

Synthesis of derivatives of 1, 2, 4-triazole-3, 5-dicarboxylic acid

  • T. N. Vereshchagina
  • V. A. Lopyrev
  • M. S. Pevzner
  • L. M. Kogan
Article

Abstract

By oxidation of 3,5-dimethyl-1,2,4-triazole the monopotassium salt of 1,2,4-triazole-3,5-dicarboxylic acid was obtained. The mononitryl of 1,2,4-triazole-3,5-dicarboxylic acid was isolated during the reaction between 3-diazo-1,2,4-triazole-5-carboxylic acid and potassium cyanide in the presence of copper cyanide. Acid hydrolysis of 3-cyano-1,2,4-triazole-5-carboxylic acid leads to the formation of 3-carbamido-5-carboxy-1,2,4-trlazole, which on esterification with methanol gives rise to 3-carbamido-5-carbomethoxy-1,2,4-triazole.

Keywords

Oxidation Copper Methanol Potassium Hydrolysis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

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    English patent no. 816531, 1959; Chemical abstracts,54, 1552, 1960.Google Scholar
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    G. I. Chipen and V. Ya. Grinshtein, Izv. AN Latv. SSR, ser. khim., 204, 1965.Google Scholar
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    E. N. Zil'berman and A. E. Kulikova, ZhOKh,29, 3039, 1959.Google Scholar
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    I. Ya. Postovskii and N. N. Vereshchagina, ZhOKh, 29, 2139, 1959.Google Scholar

Copyright information

© Consultants Bureau 1972

Authors and Affiliations

  • T. N. Vereshchagina
    • 1
    • 2
  • V. A. Lopyrev
    • 1
    • 2
  • M. S. Pevzner
    • 1
    • 2
  • L. M. Kogan
    • 1
    • 2
  1. 1.North-Western Extra-Mural Polytechnic InstituteLeningrad
  2. 2.Lensovet Leningrad Technological InstituteUSSR

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