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Saturated nitrogen-containing heterocyclic compounds

III. Synthesis and properties of 5-alkylpyrrolidones-2

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

A number of previously unknown 5-alkylpyrrolidones-2 and 1-methyl-5-alkylpyrrolidones-2 were synthesized by reductive amination of the ethyl esters of 8-ketocarboxylic acids with ammonium and methylamine in the presence of Raney nickel, ruthenium dioxide, or Raney nickel activated with ruthenium. The highest yields of 5-alkylpyrrolidones-2 were obtained when ruthenium dioxide was used as a catalyst. The acetyl derivatives of 5-alkylpyrrolidones-2 are described.

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Authors and Affiliations

  1. Chernyshevskii State University, Saratov

    A. A. Ponomarev & V. A. Sedavkina

Authors
  1. A. A. Ponomarev
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  2. V. A. Sedavkina
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Additional information

For part II, see [1].

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Ponomarev, A.A., Sedavkina, V.A. Saturated nitrogen-containing heterocyclic compounds. Chem Heterocycl Compd 5, 598–601 (1969). https://doi.org/10.1007/BF00957367

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  • DOI: https://doi.org/10.1007/BF00957367

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