Reaction of polyfluoroaromatics with o- and p- aminophenols in DMF

  • T. N. Gerasimova
  • E. F. Kolchina
  • I. Yu. Kargapolova
Organic Chemistry


  1. 1.

    The reaction of pentafluorobenzene with o- and p-aminophenols can lead to the corresponding hydroxydiarylamine (neutral medium) or to the aminodiphenyl ether (in the presence of base).

  2. 2.

    In contrast to 2,3,4,5,6-pentafluoro-2′-aminadiphenyl ether, 4-nitro-2,3,5,6-tetrafluoro-2′-aminodiphenyl ether rearranged to the isomeric 2-hydroxydiphenylamine.



Ether Aminophenol Neutral Medium Pentafluorobenzene Aminodiphenyl 
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Copyright information

© Plenum Publishing Corporation 1988

Authors and Affiliations

  • T. N. Gerasimova
    • 1
  • E. F. Kolchina
    • 1
  • I. Yu. Kargapolova
    • 1
  1. 1.Novosibirsk Institute of Organic Chemistry, Siberian BranchAcademy of Sciences of the USSRUSSR

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