Conclusions
Alkylation of alanine, phenylalanine, and glycine in the Ni(II) complexes of their Schiffs bases with S-2-N-(N′-benzylpropyl)aminobenzophenone followed by Chromatographic separation of the diastereomers has given optically pure S- and R-α-methyl-α-aminoacids.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literature cited
G. I. Chipens, V. A. Slavinskaya, D. É. Sile, et al., Izv. Akad. Nauk Latvian SSR, 259 (1985).
G. I. Chipens, L. K. Polevaya, N. I. Veretennikova, and A. Yu. Krikis, The Structures and Functions of Oligomolecular Peptides [in Russian], Zinatne (1980).
U. Schollkopf, Pure Appl. Chem.,55, 1806 (1983).
D. Seebach, M. Boes, F. Naef, and W. E. Schweizen, J. Am. Chem. Soc.,105, 5390 (1983).
M. Kolb and J. Barth, Liebigs Ann. Chem., 1688 (1983).
Yu. M. Belokon′, N. I. Chernoglazova, K. A. Kochetkov, et al., J. Chem. Soc. Chem. Communs., 171 (1985).
Yu. N. Belokon′, A. G. Bulychev, S. V. Vitt, et al., J. Am. Chem. Soc.,107, 4252 (1985).
C. J. Liu and B. E. Douglas, Inorg. Chem., 1356 (1964).
A. Gordon and R. A. Ford, Chemists' Companion, Wiley-Interscience, New York (1973).
Author information
Authors and Affiliations
Additional information
Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 12, pp. 2798–2804, December, 1987.
Rights and permissions
About this article
Cite this article
Belokon', Y.N., Chernoglazova, N.I., Bakhmutov, V.I. et al. Asymmetric synthesis of α-methylaminoacids by the alkylation of glycine, alanine, and phenylalanine in chiral Ni(II) complexes. Russ Chem Bull 36, 2595–2601 (1987). https://doi.org/10.1007/BF00957242
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00957242