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Catalytic hydrogenation of ethyl α-acetylamino-β-ketobutyrate on modified metal catalysts

  • I. P. Murina
  • A. A. Vedenyapin
  • E. I. Klabunovskii
Physical Chemistry

Conclusions

  1. 1.

    We have prepared a skeletal Cu-Pd catalyst modified with tartaric acid, on which there is 100% selectivity in the hydrogenation of ethyl α-acetylamino-β-ketobutyrate with a yield of N-acetyl-allo-threonine ethyl ester of about 90%.

     
  2. 2.

    It is shown that the nature of the metal phase of the catalysts has an effect on their activity, selectivity, and diastereoselectivity in this process.

     

Keywords

Hydrogenation Ester Ethyl Ethyl Ester Metal Catalyst 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Literature cited

  1. 1.
    A. A. Vedenyapin, I. P. Murina, T. I. Kuznetsova, and E. I. Klabunovskii, Izv. Akad. Nauk SSSR, Ser. Khim., 2584 (1986).Google Scholar
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Copyright information

© Plenum Publishing Corporation 1988

Authors and Affiliations

  • I. P. Murina
    • 1
  • A. A. Vedenyapin
    • 1
  • E. I. Klabunovskii
    • 1
  1. 1.N. D. Zelinskii Institute of Organic ChemistryAcademy of Sciences of the USSRMoscow

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