Conclusions
Trichloromethyicarbinols and their acetates react with diethylamine under phase-transfer catalysis conditions to give diethylamides of α-diethylaminocarboxylic acids. The same products are formed in the reaction of aldehyde acylals with chloroform and diethylamine in the 50% aqueous NaOH-BTEAC phase-transfer catalytic system.
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Literature cited
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Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 5, pp. 1190–1192, May, 1986.
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Kryshtal', G.V., Zhdankina, G.M. & Yanovskaya, L.A. Synthesis of diethylamides of α-diethylaminocarboxylic acids using α-trichloromethylcarbinols and their acetates under phase-transfer catalysis conditions. Russ Chem Bull 35, 1081–1083 (1986). https://doi.org/10.1007/BF00955387
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DOI: https://doi.org/10.1007/BF00955387