Reaction of methyl esters of fluorinated β-keto acids with hydroxyl-containing nucleophiles
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When hydroxyl-containing nucleophiles add to fluorinatedβ-keto esters they add to the enol form of the β-keto ester.
An increase in the length of the fluoroalkyl substituent from HCF2 to n-C4F9, and also an increase in the size of the hydroxyl-containing nucleophile substituent, both lead to a decrease in the amount of the adduct for the fluorinatedβ-keto esters when they are reacted with hydroxyl-containing nucleophiles.
KeywordsMethyl Ester Adduct Methyl Ester Enol
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- 1.K. I. Pashkevich, V. I. Saloutin, and I. Ya. Postovskii, Usp. Khim.,50, 325 (1981).Google Scholar
- 2.K. I. Pashkevich, A. N. Fomin, V. I. Saloutin, D. V. Bazhenov, and Yu. K. Grishin, Izv. Akad. Nauk SSSR, Ser. Khim., 1359 (1982).Google Scholar
- 3.F. Camps, J. Coll, A. Messequer, and A. Roca, Tetrahedron,33, 1637 (1977).Google Scholar
- 4.A. L. Henne, M. S. Newman, L. L. Quill, and R. N. Staniforth, J. Am. Chem. Soc.,69, 1819 (1947).Google Scholar