Synthesis and anticholine esterase properties of S-ethynyl esters of thiophosphoric acids

  • N. N. Godovikov
  • L. A. Vikhreva
  • K. K. Babasheva
  • O. E. Sherstobitov
  • E. K. Balashova
  • L. I. Kugusheva
  • V. I. Rozengart
  • A. P. Brestkin
  • M. I. Kabachnik
Geminal Systems
  • 17 Downloads

Conclusions

Introduction of acetylenic bond into the α-position of the thioester group of thiophosphoric acids leads to a sharp intensification of the ability of these compounds to inhibit choline esterase of different origins.

Keywords

Ester Choline Choline Esterase Inhibit Choline Esterase Thioester 

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Literature cited

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Copyright information

© Plenum Publishing Corporation 1984

Authors and Affiliations

  • N. N. Godovikov
    • 1
    • 2
  • L. A. Vikhreva
    • 1
    • 2
  • K. K. Babasheva
    • 1
    • 2
  • O. E. Sherstobitov
    • 1
    • 2
  • E. K. Balashova
    • 1
    • 2
  • L. I. Kugusheva
    • 1
    • 2
  • V. I. Rozengart
    • 1
    • 2
  • A. P. Brestkin
    • 1
    • 2
  • M. I. Kabachnik
    • 1
    • 2
  1. 1.A. N. Nesmeyanov Institute of Heteroorganic CompoundsAcademy of Sciences of the USSRMoscow
  2. 2.I. M. Sechenov Institute of Evolutional Physiology and BiochemistryAcademy of Sciences of the USSRLeningrad

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