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Synthesis and anticholine esterase properties of S-ethynyl esters of thiophosphoric acids

  • N. N. Godovikov
  • L. A. Vikhreva
  • K. K. Babasheva
  • O. E. Sherstobitov
  • E. K. Balashova
  • L. I. Kugusheva
  • V. I. Rozengart
  • A. P. Brestkin
  • M. I. Kabachnik
Geminal Systems
  • 18 Downloads

Conclusions

Introduction of acetylenic bond into the α-position of the thioester group of thiophosphoric acids leads to a sharp intensification of the ability of these compounds to inhibit choline esterase of different origins.

Keywords

Ester Choline Choline Esterase Inhibit Choline Esterase Thioester 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Literature cited

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Copyright information

© Plenum Publishing Corporation 1984

Authors and Affiliations

  • N. N. Godovikov
    • 1
    • 2
  • L. A. Vikhreva
    • 1
    • 2
  • K. K. Babasheva
    • 1
    • 2
  • O. E. Sherstobitov
    • 1
    • 2
  • E. K. Balashova
    • 1
    • 2
  • L. I. Kugusheva
    • 1
    • 2
  • V. I. Rozengart
    • 1
    • 2
  • A. P. Brestkin
    • 1
    • 2
  • M. I. Kabachnik
    • 1
    • 2
  1. 1.A. N. Nesmeyanov Institute of Heteroorganic CompoundsAcademy of Sciences of the USSRMoscow
  2. 2.I. M. Sechenov Institute of Evolutional Physiology and BiochemistryAcademy of Sciences of the USSRLeningrad

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