Conclusions
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1.
The reaction of esters of 3-phenyl-3-chloro-2-ketopropionic acid with sodium alcoholates in alcohol (methanol or ethanol) at reflux leads to the formation of an ester of 2,5-diketo-3,4-diphenyl-3-methoxyhexanedioic or 2,5-diketo-3,4-diphenyl-3-ethoxyhexanedioic acid.
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2.
The reactions of esters of 3-phenyl-3-chloro-2-ketopropionic acid with the corresponding sodium alcoholates in dilute solution at 0‡C give the product of the substitution of chlorine by an alkoxy group in quantitative yield.
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Literature cited
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Translated from Izvestiya Akadamii Nauk SSSR, Seriya Khimicheskaya, No. 4, pp. 962–964, April, 1989.
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Mamedov, V.A., Nuretdinov, I.A., Efremov, Y.Y. et al. Reactions of esters of 3-phenyl-3-chloro-2-ketopropionic acid with sodium alcoholates. Russ Chem Bull 38, 867–869 (1989). https://doi.org/10.1007/BF00953311
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DOI: https://doi.org/10.1007/BF00953311