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Ir gene control of T and B cell responses to determinants in poly(Glu, Ala, Phe)

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Abbreviations

GA:

poly(Glu60, Ala40)

GT:

poly(Glu50, Tyr50)

GAT:

poly(Glu60, Ala30, Tyr10)

GLPhe:

poly(Glu55, Lys36, Phe9)

GLA:

poly(Glu36, LyS24, Ala40)

GAPhe:

poly(Glu54, Ala34, Phe12)

GLT:

poly(GLu51, Lys34, Tyr15)

SRBC:

sheep red blood cell

References

  • Babu, U. M. and Maurer, P. H.: The expression of anti-poly (\(\underset{\raise0.3em\hbox{$\smash{\scriptscriptstyle-}$}}{L} \)Glu60,\(\underset{\raise0.3em\hbox{$\smash{\scriptscriptstyle-}$}}{L} \)Phe40 idiotypic determinants dictated by the gene products in the major histocompatibility complex (H-2q).J. Exp. Med. 154: 649–658, 1981

    Google Scholar 

  • Babu, U. M., Maurer, P. H., Merryman, C. F., and Anderson, J. M.: Plaque forming cell assay to measure responses in mice to the random copolymer (Glu60Phe40).Immunol. Commun. 8: 531–538, 1979a

    Google Scholar 

  • Babu, U. M., Lai, C. H., Maurer, P. H., and Merryman, C. F.: Immune response of mice to GLA measured by plaque forming and T cell proliferative assays (Abstr.).Fed. Proc. 38: 2264, 1979b

    Google Scholar 

  • Benacerraf, B. and Katz, D. H. The nature and function of histocompatibility-linked immune response genes.In B. Benacerraf (ed.):Immunogenetics and Immunodeficiency, pp. 117–177, University Park Press, Baltimore 1975

    Google Scholar 

  • Martin, W. J., Maurer, P. H., and Benacerraf, B.: Genetic control of immune responsiveness to a glutamic acid, alanine, tyrosine copolymer in mice. I. Linkage of responsiveness to H-2 genotype.J. Immunol. 107: 715–718, 1971

    Google Scholar 

  • Maurer, P. H.: Immune response of inbred guinea pigs to the random terpolymers poly (Glu57, Lys38, Tyr5) and poly (Glu51, Lys34, Tyr15).Proc. Soc. Exp. Biol. Med. 147: 640–643, 1974

    Google Scholar 

  • Maurer, P. H., Merryman, C. F., Lai, C. H., and Ganfield, D. J.: Dependence of immune responses of “nonresponder” H-28 mice on determinant concentration in poly(Glu60A1a30Tyr10) and on complementation between nonresponder mice of the same H-2p haplotype.Immunochemistry 15: 737–744, 1978

    Google Scholar 

  • McDevitt, H.O. and Chinitz, A.: Genetic control of the antibody response: Relationship between immune response and histocompatibility (H-2 type).Science 163: 1207–1210, 1969

    Google Scholar 

  • Merryman, C. F. and Maurer, P. H.: Genetic control of immune response to glutamic acid, alanine, tyrosine containing copolymers in mice.J. Immunol. 108: 135–141, 1972

    Google Scholar 

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Authors and Affiliations

  1. Department of Biochemistry, Thomas Jefferson University, 1020 Locust Street, 19107, Philadelphia, PA

    Uma Mahesh Babu, Chang-Hai Lai & Paul H. Maurer

Authors
  1. Uma Mahesh Babu
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  2. Chang-Hai Lai
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  3. Paul H. Maurer
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Babu, U.M., Lai, CH. & Maurer, P.H. Ir gene control of T and B cell responses to determinants in poly(Glu, Ala, Phe). Immunogenetics 18, 303–306 (1983). https://doi.org/10.1007/BF00952968

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  • DOI: https://doi.org/10.1007/BF00952968

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