Reaction of hypochlorous acid with 2,6-di-tert-butylphenol and its derivatives
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Regioselectivity was established for the chlqrination of sterically hindered phenols by HOCl. The direction of chlorination is dependent on the temperature, acidity of the medium, and electronic effect of the para substituent.
KeywordsPhenol Acidity HOCl Electronic Effect Hypochlorous Acid
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