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cis- and trans-4-aminocyclohexylacetic acids and their diethylenimido(thio)phosphoryl derivatives

  • K. I. Karpavichyus
  • A. I. Palaima
  • I. L. Knunyants
Organic Chemistry
  • 52 Downloads

Conclusions

  1. 1.

    The stereospecific hydrogenation of p-nitrophenylacetic acid was run on Raney Ni catalyst to give chiefly the trans isomer of 4-aminocyclohexylacetic acid. The cis and trans isomers were separated as the hydrochlorides.

     
  2. 2.

    We synthesized the N-phthalyl, N-dichloro(thio)phosphoryl, N-diethylenimido(thio)phosphoryl, and N-tetramethyldiamido(thio)phosphoryl derivatives of cis- and trans-4-aminocyclohexylacetic acid.

     

Keywords

Hydrogenation Hydrochloride Thio Trans Isomer Phosphoryl 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Literature cited

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    A. I. Palaima, R. A. Poshkene, K. I. Karpavichyus, O. V. Kil'disheva, and I. L. Knunyants, Izv. Akad. Nauk SSSR, Ser. Khim.,1977, 195.Google Scholar
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    N. F. Zakharova, K. I. Karpavichyus, R. A. Poshkene, and A. I. Palaima, Tr. Akad. Nauk Lit. SSR, Ser. C,4(76), 131 (1976).Google Scholar
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    N. F. Smirnova, I. S. Monakhova, G. I. Rybina, V. G. Kharchenko, K. I. Karpavichyus, and A. I. Palaima, Zh. Org. Khim.,12, 661 (1976).Google Scholar
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    Organic Syntheses [Russian translation]. Coll. Vol. 3, IL (1952), p. 338.Google Scholar

Copyright information

© Plenum Publishing Corporation 1981

Authors and Affiliations

  • K. I. Karpavichyus
    • 1
    • 2
  • A. I. Palaima
    • 1
    • 2
  • I. L. Knunyants
    • 1
    • 2
  1. 1.Institute of Heteroorganic CompoundsAcademy of Sciences of the USSRMoscow
  2. 2.Institute of BiochemistryAcademy of Sciences of the Lithuanian SSRVilnius

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