Conclusions
Acetylenyl-N-methylpyrazolecarboxylic acids containing an acetylenic substituent and a carboxyl group on adjacent carbon atoms cyclize in pyridine in the presence of copper phenylacetylenide to pyranopyrazoles. The same compounds are obtained by the acetylenide cyclocondensation of the appropriate iodopyrazolecarboxylic acids, but at a much lower rate.
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Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 6, pp. 1342–1348, June, 1981.
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Shvartsberg, M.S., Vasilevskii, S.F., Anisimova, T.V. et al. Cyclization of acetylenylpyrazolecarboxylic acids. Russ Chem Bull 30, 1071–1076 (1981). https://doi.org/10.1007/BF00950297
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DOI: https://doi.org/10.1007/BF00950297