Reactions of carbonyl compounds in the presence of phase-transition catalysts. 6. The alkylation and ketonic decomposition of acetoacetic and prenylacetoacetic esters
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We measured the initial rates for the major reactions proceeding in a catalytic two-phase system in the alkylation of acetoacetic ester (AAE) by 1-chloro-3-methyl-2-butene and it was shown that the formation of methylheptenone occurs in the decarboxylation of prenylacetoacetic ester (I) and not as a result of the alkylation of acetone formed from AAE.
The initial rates of alkylation and ketonic decomposition of AAE and (I) were measured and substituted AAE was found more active in these reactions.
The potassium derivatives of the ketoesters and the potassium salts of the ketoacids are formed in the reaction of 50% aq. KOH with AAE and (I).
KeywordsEster Potassium Acetone Carbonyl Alkylation
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